Exenatide and Metformin Improve Serum Indices and Intestinal Flora in patients with Type 2 Diabetes Mellitus and Non-Alcoholic Fatty Liver Disease Authors Xiaojie Jiang Department of Pharmaceutical Preparation, The Hangzhou Xixi Hospital Affiliated to Zhejiang University School of Medicine, China Tingting Shi Department of Pharmaceutical Preparation, The Hangzhou Xixi Hospital Affiliated to Zhejiang University School of Medicine, China Dan Han Department of Pharmacy, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, China Juan Chen Department of Endocrine, The Hangzhou Xixi Hospital Affiliated to Zhejiang University School of Medicine, China DOI: https://doi.org/10.47391/JPMA.8295 Keywords: Type 2 diabetes mellitus, Non-alcoholic fatty liver disease, Metformin, Exenatide, Intestinal flora Abstract The aim of the study was to investigate the influence of Exenatide combined with Metformin on fasting blood glucose, postprandial glucose, triglycerides, total cholesterol, alanine aminotransferase, aspartate aminotransferase, and intestinal flora in type 2 diabetes mellitus cases with non-alcoholic fatty liver disease. A total of 128 type 2 diabetes mellitus patients with non-alcoholic fatty liver disease, diagnosed from January 2019 to January 2022, were included and randomly assigned to either Group A (n=64) or Group B (n=64). Group A received Metformin, while Group B received Exenatide injection and Metformin. After 24 weeks of treatment, blood glucose indices (fasting blood glucose and postprandial glucose), blood lipid indices (triglycerides and total cholesterol), liver function indices (alanine aminotransferase and aspartate aminotransferase) were all lower in Group B than in Group A (P < 0.001 for all). ---Continue Downloads Full Text Article Published 2023-12-24 How to Cite Jiang, X., Shi, T., Han, D., & Chen, J. (2023). Exenatide and Metformin Improve Serum Indices and Intestinal Flora in patients with Type 2 Diabetes Mellitus and Non-Alcoholic Fatty Liver Disease. Journal of the Pakistan Medical Association, 74(1), 138–140. https://doi.org/10.47391/JPMA.8295 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 74 No. 1 (2024): JANUARY Section SHORT COMMUNICATION License Copyright (c) 2023 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.