Application of multigene panel detection in breast cancer Authors Yuan Zhao Department of Oncology, Puer People's Hospital, China Dun Xiong Department of Oncology, Puer People's Hospital, China Bo Yang Department of Oncology, Puer People's Hospital, China Shaocai Xia Department of Oncology, Puer People's Hospital, China Xinzhi Zhang Department of Oncology, Puer People's Hospital, China DOI: https://doi.org/10.47391/JPMA.6830 Keywords: Multigene panel testing, Breast cancer, Oncotype Dx, MammaPrint, Endopredict, PAM50, BCI, CancerSeek Abstract Precision medicine will be the direction of future medical development, especially in cancer diagnosis and treatment. With the deepening of breast cancer-related research, new factors related to diagnosis, treatment and prognosis are constantly being discovered. Researchers combine different factors to form a multigene panel testing, guiding clinicians' decision-making. The application scope of multigene panel detection is constantly expanding. At present, it has been tried in the prognosis evaluation of lymph node-positive and human epidermal growth factor receptor 2-positive breast cancer patients and the early screening of breast cancer. With continuous technological advancement, there will be broader application prospects in the future. The current narrative review was planned to evaluate the recent advances in applying multigene panel testing in breast cancer cases. Key Words: Multigene panel testing, Breast cancer, Oncotype Dx, MammaPrint, Endopredict, PAM50, BCI, CancerSeek. Downloads Full Text Article Published 2023-08-15 How to Cite Zhao, Y., Xiong, D., Yang, B., Xia, S., & Zhang, X. (2023). Application of multigene panel detection in breast cancer. Journal of the Pakistan Medical Association, 73(9), 1862–1868. https://doi.org/10.47391/JPMA.6830 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 73 No. 9 (2023): SEPTEMBER Section Narrative Review License Copyright (c) 2023 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.