Application of multigene panel detection in breast cancer

Authors

  • Yuan Zhao Department of Oncology, Puer People's Hospital, China
  • Dun Xiong Department of Oncology, Puer People's Hospital, China
  • Bo Yang Department of Oncology, Puer People's Hospital, China
  • Shaocai Xia Department of Oncology, Puer People's Hospital, China
  • Xinzhi Zhang Department of Oncology, Puer People's Hospital, China

DOI:

https://doi.org/10.47391/JPMA.6830

Keywords:

Multigene panel testing, Breast cancer, Oncotype Dx, MammaPrint, Endopredict, PAM50, BCI, CancerSeek

Abstract

Precision medicine will be the direction of future medical development, especially in cancer diagnosis and treatment. With the deepening of breast cancer-related research, new factors related to diagnosis, treatment and prognosis are constantly being discovered. Researchers combine different factors to form a multigene panel testing, guiding clinicians' decision-making. The application scope of multigene panel detection is constantly expanding. At present, it has been tried in the prognosis evaluation of lymph node-positive and human epidermal growth factor receptor 2-positive breast cancer patients and the early screening of breast cancer. With continuous technological advancement, there will be broader application prospects in the future. The current narrative review was planned to evaluate the recent advances in applying multigene panel testing in breast cancer cases.

Key Words: Multigene panel testing, Breast cancer, Oncotype Dx, MammaPrint, Endopredict, PAM50, BCI, CancerSeek.

Published

2023-08-15

How to Cite

Zhao, Y., Xiong, D., Yang, B., Xia, S., & Zhang, X. (2023). Application of multigene panel detection in breast cancer. Journal of the Pakistan Medical Association, 73(9), 1862–1868. https://doi.org/10.47391/JPMA.6830

Issue

Section

Narrative Review