A morphological study comparing heart size measurement on chest radiograph with echocardiography in local population Authors Ahmed Ali Khan Department of Anatomy, Bolan Medical College, Quetta, Pakistan Aisha Qamar Department of Anatomy, Bahria University Medical and Dental College, Karachi, Pakistan DOI: https://doi.org/10.47391/JPMA.6089 Abstract Objectives: To investigate heart size on chest X-ray via cardiothoracic ratio, and to correlate it with echocardiographic measurements. Method: The comparative analytical, cross-sectional study was conducted at the Pakistan Navy Station Shifa Hospital, Karachi, between January 2021 and July 2021. The radiological parameters were measured on chest X-rays posterior-anterior view, and the echocardiographic parameters were measured using 2-dimensional transthoracic echocardiography. The absence or presence of cardiomegaly on both imaging modalities was modelled as a binary categorical variable and compared. Data was analysed using SPSS 23. Results: Of the 79 participants, 44(55.7%) were males and 35(44.3%) were females. The mean age of the sample was 52.71±14.54 years. There were 28(35.44%) enlarged hearts on chest X-ray and 46(58.22%) on echocardiography. The sensitivity and specificity of chest X-ray were 54.35% and 90.90%, respectively. The positive and negative predictive values were 89.28% and 58.82%, respectively. The accuracy of chest X-ray in identifying an enlarged heart was 69.62%. Conclusion: The cardiac silhouette on a chest X-ray could demonstrate heart size through simple measurements with high specificity and reasonable accuracy. However, a normal heart size on chest X-ray may not have a normal function. Key Words: Heart size, Cardiomegaly, Cardiothoracic ratio, Chest X-ray, PA view, Transthoracic echocardiography. Author Biography Aisha Qamar, Department of Anatomy, Bahria University Medical and Dental College, Karachi, Pakistan MBBS, MPhil., Professor, Department of Anatomy, Bahria University Medical & Dental College, Karachi Downloads Full Text Article Published 2023-02-15 How to Cite Ahmed Ali Khan, & Aisha Qamar. (2023). A morphological study comparing heart size measurement on chest radiograph with echocardiography in local population. Journal of the Pakistan Medical Association, 73(2), 302–306. https://doi.org/10.47391/JPMA.6089 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 73 No. 2 (2023): February Section RESEARCH ARTICLE