Mammary analogue secretory carcinoma of the parotid gland—a rare tumour entity

Authors

  • Syeda Tehmina Junaid Department of ENT, Head and Neck Surgery, Dow Medical College, Dow University of Health Sciences and Civil Hospital, Karachi, Pakistan
  • Soima Ali Muhammad 4th Year MBBS Student, Dow University of Health Sciences, Karachi, Pakistan
  • Zeba Ahmed Department of ENT, Head and Neck Surgery, Dow Medical College, Dow University of Health Sciences and Civil Hospital, Karachi, Pakistan
  • Khubeb Department of ENT, Civil Hospital, Karachi, Pakistan
  • Rajesh Kumar Vasandani Department of ENT, Head and Neck Surgery, Dow Medical College, Dow University of Health Sciences and Civil Hospital, Karachi, Pakistan
  • Jawad Ahmed Department of Internal Medicine, Dow University of Health Sciences, Karachi, Pakistan

DOI:

https://doi.org/10.47391/JPMA.5472

Abstract

Mammary analogue secretory carcinoma (MASC) is a salivary gland tumour with low-grade potential and specific FTV6 derangement having translocation of chromosomes t (12;15) (p13;q25). It shares a similar morphological as well as an immunohistochemical profile with secretory carcinoma (SC) of the breast making it a diagnostic enigma.

In this report, we discuss the case of a 65-year-old male patient, who presented with a complaint of right-sided facial swelling. To rule out the differential, he underwent various diagnostic modalities, including magnetic resonance imaging, fine-needle aspiration and it’s the tumour’s microscopic and immunohistochemical properties were also reviewed. Parotidectomy along with concurrent chemo-radiotherapy was performed to eradicate the growing mass.

Keywords: Mammary analogue secretory carcinoma, immunohistochemical, Parotidectomy.

Author Biographies

Syeda Tehmina Junaid, Department of ENT, Head and Neck Surgery, Dow Medical College, Dow University of Health Sciences and Civil Hospital, Karachi, Pakistan

Assistant professor, Department of ENT, Head and neck surgery, DMC, DUHS and Civil hospital karachi.

Zeba Ahmed, Department of ENT, Head and Neck Surgery, Dow Medical College, Dow University of Health Sciences and Civil Hospital, Karachi, Pakistan

Professor and Head of Department of ENT,Head and Neck Surgery,Unit-II,DMC,DUHS and Civil Hospital Karachi.

Khubeb, Department of ENT, Civil Hospital, Karachi, Pakistan

Resident (R2) of ENT department of ENT Unit-II,Civil Hospital Karachi.

Rajesh Kumar Vasandani, Department of ENT, Head and Neck Surgery, Dow Medical College, Dow University of Health Sciences and Civil Hospital, Karachi, Pakistan

Assistant Professor Department of  ENT,Head and Neck Surgery,Unit-II,DMC,DUHS and Civil Hospital Karachi.

Jawad Ahmed, Department of Internal Medicine, Dow University of Health Sciences, Karachi, Pakistan

 

House-Officer at Civil Hospital Karachi.

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Published

2023-02-15

How to Cite

Syeda Tehmina Junaid, Soima Ali Muhammad, Zeba Ahmed, Khubeb, Rajesh Kumar Vasandani, & Jawad Ahmed. (2023). Mammary analogue secretory carcinoma of the parotid gland—a rare tumour entity. Journal of the Pakistan Medical Association, 72(2), 412–415. https://doi.org/10.47391/JPMA.5472

Issue

Vol. 72 No. 2 (2022): FEBRUARY

Section

CASE REPORT

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