Distribution and antimicrobial susceptibility profile of bacterial and fungal pathogens isolated from burn wounds in hospitalized patients

Abstract

Abstract

Objective: Current study was designed to isolate the pathogens from burn wounds and determine the antibiogram of these isolates.

Methods: A total of 85 samples were collected from burn patients with the history of different weeks of hospitalization in various public and private hospitals of Faisalabad during September 2017-July 2019 and shifted to Department of Microbiology, Government College University, Faisalabad for further processing. Isolation and identification of the pathogens was done through conventional microbiological procedures. Disc diffusion method was used for the determination of antibacterial and antifungal activity.

Results: A total of 91% samples were found positive for the presence of bacterial or fungal pathogens. Commonly isolated pathogens were Staphylococcus aureus (21%), Pseudomonas aeruginosa (21%), Bacillus subtilis (16%), Escherichia coli (14%), Candida albicans (12%), Aspergillus flavus (9%) and Salmonella Typhi (7%). Highest resistance was found against S. aureus and P. aeruginosa. Cefotaxime was the least effective antibiotic, while Gentamicin and Amphotericin-B were the most effective antimicrobial drugs against bacterial and fungal pathogens, respectively. Continuous....