Synchronous locally advanced rectal and prostate cancer: Dual tracer imaging with 18F-FDG-PET/CT and 68Ga-PMSA PET/CT Authors Sharjeel Usmani Department of Radiology and Nuclear Medicine, Sultan Qaboos Comprehensive Cancer Care and Research Centre (SQCCCRC), University Medical City, Muscat Oman. Khulood Al Riyami Department of Radiology and Nuclear Medicine, Sultan Qaboos Comprehensive Cancer Care and Research Centre (SQCCCRC), University Medical City, Muscat Oman. Syeda Sara Tajammul Department of Radiology and Nuclear Medicine, Sultan Qaboos Comprehensive Cancer Care and Research Centre (SQCCCRC), University Medical City, Muscat Oman. Anjali Jain Department of Radiology and Nuclear Medicine, Sultan Qaboos Comprehensive Cancer Care and Research Centre (SQCCCRC), University Medical City, Muscat Oman. Najeeb Ahmed Hull Molecular Imaging and Research Center, UK DOI: https://doi.org/10.47391/JPMA.26-75 Abstract Synchronous rectal and prostate malignancies are uncommon. Early diagnosis, accurate staging, and characterization of tumours are essential for selecting patient-tailored therapy. The origin of metastatic disease in synchronous cases presents a challenge for conventional imaging modalities but advances in molecular imaging have addressed this limitation. We report the case of a 72-year-old male with synchronous prostate and rectal cancer. Adoption of a dual PET/CT approach is essential for accurate staging and patient management. The combined molecular imaging approach significantly influenced staging and enabled individualized multidisciplinary management tailored to the biological behaviour and extent of each primary tumour. Keywords: 68Ga-PSMA PET/CT; 18F-FDG-PET/CT; synchronous tumours; prostate cancer Downloads Full Text Article Published 2026-08-26 How to Cite Sharjeel Usmani, Khulood Al Riyami, Syeda Sara Tajammul, Anjali Jain, & Najeeb Ahmed. (2026). Synchronous locally advanced rectal and prostate cancer: Dual tracer imaging with 18F-FDG-PET/CT and 68Ga-PMSA PET/CT. Journal of the Pakistan Medical Association, 76(09), 1584–1585. https://doi.org/10.47391/JPMA.26-75 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 76 No. 09 (2026): September Section IMAGING CORNER License Copyright (c) 2026 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.