Trials and tribulations of overcoming xenograft rejection Authors Muhammad M Mohiuddin 1Program in Cardiac Xenotransplantation University of Maryland School of Medicine, Baltimore, Maryland, 2International Xenotransplantation Association (IXA). DOI: https://doi.org/10.47391/JPMA.DUHS-25-01 Abstract Throughout the world, there are millions of patients with terminal organ failure who are waiting for a human organ for transplantation. Over the last 20 years, due to improvement in our understanding of transplant organ rejection and progressively improved immunosuppression regimens, organ transplants have provided a significant extension of life. This success has saved many lives, but at the same time, due to increased public awareness and demand, it has created an acute shortage of organ donors.1 Not every donor organ can be used for transplantation, and multiple factors contribute to the selection of a transplantable organ based on the stringent selection criteria of these donors and the organs. Therefore, a similar tough criterion is applied to the recipients based on the urgency of the organ requirement. Continued... Downloads Full Text Article Published 2025-10-01 How to Cite Muhammad M Mohiuddin. (2025). Trials and tribulations of overcoming xenograft rejection. Journal of the Pakistan Medical Association, 75(10 (Supp-3), S–1. https://doi.org/10.47391/JPMA.DUHS-25-01 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 75 No. 10 (Supp-3) (2025): First International Conference on Transplantation Section EDITORIAL License Copyright (c) 2026 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.