Diachronous primary Neuroendocrine tumour of the mediastinum: Dual FDG and DOTA avidity on PET/CT Authors Nadia Nazir Department of Radiology, Ayesha Zubair Department of Nuclear Medicine; Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan.. Aamna Hassan Department of Nuclear Medicine; Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan.. Kashif Saddique Department of Radiology, DOI: https://doi.org/10.47391/JPMA.26-32 Abstract Primary neuroendocrine tumours (NETs) of the mediastinum are exceedingly rare, accounting for a small fraction of thoracic neoplasms. Their biological behaviour is heterogeneous, ranging from indolent to highly aggressive depending upon their histological grading. Dual-tracer PET/CT imaging with fluorodeoxyglucose (FDG) and gallium-68 DOTA-conjugated peptides provides complementary information, reflecting heterogeneity of tumour including both metabolic activity and somatostatin receptor expression. Downloads Full Text Article Published 2026-03-26 How to Cite Nadia Nazir, Ayesha Zubair, Aamna Hassan, & Kashif Saddique. (2026). Diachronous primary Neuroendocrine tumour of the mediastinum: Dual FDG and DOTA avidity on PET/CT. Journal of the Pakistan Medical Association, 76(04), 618–619. https://doi.org/10.47391/JPMA.26-32 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 76 No. 04 (2026): APRIL Section IMAGING CORNER License Copyright (c) 2026 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.