18F-FDG PET/CT in Malignant Peripheral Nerve Sheath Tumours: Insights and Clinical Implications Authors Sharjeel Usmani Department of Radiology and Nuclear Medicine, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), Muscat Oman; Hull York Medical School, Hull, UK; Khulood Al Riyami Department of Radiology and Nuclear Medicine, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), Muscat Oman; Shah P. Numani Department of Radiology, Carl T Hayden VA Medical Center, Phoenix USA; Anjali Jain Department of Radiology and Nuclear Medicine, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), Muscat Oman; Subash Chand Kheruka Department of Radiology and Nuclear Medicine, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), Muscat Oman; Najeeb Ahmed Hull York Medical School, Hull, UK; Muhammad Shahzad Shamim Section of Neurosurgery, Aga Khan University Hospital, Karachi, Pakistan. DOI: https://doi.org/10.47391/JPMA.25-39 Abstract Malignant peripheral nerve sheath tumours (MPNSTs) arevery rare, aggressive soft-tissue neoplasms developing from and involving the peripheral nerve sheath. MPNSTs are difficult to diagnose and treat and they contribute to significant morbidity and mortality for patients. 18F-FDGPET/CT is valuable in diagnosing and staging as well as guiding therapeutic interventions, especially therapy response assessment in MPNST. As the incidence is very low, a valid statement at this point with respect to its role in patient management and optimal care is not defined.The current review will venture to use the available literature to define a role of this modality in the various aspects of management of MPNST.Keywords: 18F-FDG PET/CT; Malignant peripheral nervesheath tumours; PET/CT; neurofibromatosis; soft-tissuesarcoma Downloads Full Text Article Published 2025-04-27 How to Cite Sharjeel Usmani, Khulood Al Riyami, Shah P. Numani, Anjali Jain, Subash Chand Kheruka, Najeeb Ahmed, & Muhammad Shahzad Shamim. (2025). 18F-FDG PET/CT in Malignant Peripheral Nerve Sheath Tumours: Insights and Clinical Implications. Journal of the Pakistan Medical Association, 75(05), 834–836. https://doi.org/10.47391/JPMA.25-39 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 75 No. 05 (2025): MAY Section EVIDENCE BASED NEURO-ONCOLOGY License Copyright (c) 2025 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.