Nandrolone (17-Nortestosterone) And Glucose Metabolism: From Ugly Duckling To Handsome Swan

Authors

  • Sanjay Kalra Department of Endocrinology, Bharti Hospital, Karnal, India; University Center for Research & Development, Chandigarh University, Mohali, India
  • Atul Dhingra Department of Endocrinology, Dr SS Tantia Medical College Hospital & Research Centre, Sriganganagar, India
  • Nitin Kapoor Department of Endocrinology, Diabetes and Metabolism, Christian Medical College, Vellore, India; Non communicable disease unit, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia

DOI:

https://doi.org/10.47391/JPMA.25-27

Abstract

Glucosarcopenia, or sarcopenia coexisting with diabetes,is a common condition. Caused by various factors,including poor glucose control, as well as some glucoseloweringtherapies, sarcopenia negatively impacts qualityof life and long-term health. Nandrolone, or 19-nortestosterone, is a selective anabolic receptormodulator (SARM), classified as an anabolic-androgenicsteroid (AAS). A review of its pharmacological propertiessuggests that it may be used as therapy for sarcopenia,along with medical nutrition therapy and resistanceexercise training. This review suggests a practical andpragmatic approach towards ensuring safe and smartusage of nandrolone in glucosarcopenia management.

Keywords: Anabolic steroid, androgenic steroid,diabetes, glucosarcopenia, muscle health,musculoskeletal health, sarcopenia

Published

2025-03-18

How to Cite

Sanjay Kalra, Atul Dhingra, & Nitin Kapoor. (2025). Nandrolone (17-Nortestosterone) And Glucose Metabolism: From Ugly Duckling To Handsome Swan. Journal of the Pakistan Medical Association, 75(04), 655–657. https://doi.org/10.47391/JPMA.25-27

Issue

Section

RECENT ADVANCES IN ENDOCRINOLOGY