Intramedullary Spinal Cord Metastasis in Spinal Ependymomas Authors Zanib Javed Department of Surgery, Aga Khan University Hospital, Karachi Pakistan Raheema Sadiq Department of Surgery, Aga Khan University Hospital, Karachi Pakistan Hania Fatima Department of Surgery, Aga Khan University Hospital, Karachi Pakistan Muhammad Shahzad Shamim Department of Surgery, Aga Khan University Hospital, Karachi Pakistan DOI: https://doi.org/10.47391/JPMA.25-22 Abstract Drop metastasis, or intramedullary spinal cord metastasis(ISCM), is a rare condition accounting 0.9%–5% of CNS orspinal metastases. It arises from tumour cell disseminationthrough cerebrospinal fluid (CSF), often affecting thethoracic and lumbar spine. Clinical features include rapidlyprogressive neurological deficits, limb weakness, sensoryloss, and pain. Diagnosing drop metastasis is challengingand MRI with gadolinium remains the gold standardmodality for investigation. Surgical resection followed byradiotherapy remains the primary treatment option,whereas chemotherapy serves a palliative role in cases ofrecurrence or disseminated metastases. Keywords: Ependymomas, Drop metastases, Radiotherapy Downloads Full Text Article Published 2025-02-23 How to Cite Zanib Javed, Raheema Sadiq, Hania Fatima, & Muhammad Shahzad Shamim. (2025). Intramedullary Spinal Cord Metastasis in Spinal Ependymomas. Journal of the Pakistan Medical Association, 75(03), 509–511. https://doi.org/10.47391/JPMA.25-22 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 75 No. 03 (2025): MARCH Section EVIDENCE BASED NEURO-ONCOLOGY License Copyright (c) 2025 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.