Adrenal Asthenia Authors Sanjay Kalra Department of Endocrinology, Bharti Hospital, Karnal, India; University Center for Research & Development, Chandigarh University, Mohali, India; Atul Dhingra Department of Endocrinology, Dr SS Tantai Medical College Hospital & Research Centre, Sriganganagar, India; Nitin Kapoor Department of Endocrinology, Diabetes and Metabolism, Christian Medical College, Vellore, India; Noncommunicable disease unit, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia. DOI: https://doi.org/10.47391/JPMA.25-18 Abstract The terms ‘adrenal asthenia’, ‘adrenal fatigue’ and ‘adrenalburnout’, sometimes used in lay language, are not a part ofthe medical or endocrine lexicon. In this opinion piece, weexplore the relevance of adrenal asthenia and describe howit can be used in different clinical situations, with varyingconnotations. Adrenal asthenia may refer to adrenocorticalinsufficiency, increased parasympathetic or reducedadrenergic tone, or fatigue due to excessive andcontinuous exposure to stress. It may be mediated byhypoglycaemia or dyselectrolytaemia. The term adrenalasthenia has important clinical and public health advantages. Keywords: Adrenal, Addison’s disease, adrenalinsufficiency, person centred care, psychosocial aspects Downloads Full Text Article Published 2025-02-23 How to Cite Sanjay Kalra, Atul Dhingra, & Nitin Kapoor. (2025). Adrenal Asthenia. Journal of the Pakistan Medical Association, 75(03), 498–500. https://doi.org/10.47391/JPMA.25-18 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 75 No. 03 (2025): MARCH Section RECENT ADVANCES IN ENDOCRINOLOGY License Copyright (c) 2025 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.