A 10-year follow-up of therapeutic rehabilitation in a child with LMNA-associated congenital muscular dystrophy: a case report Authors Zhimei Liu Department of Rehabilitation Medicine, College of Physical Education, Yangzhou University, Yangzhou, China Shuo Zhao Department of Children Rehabilitation, Yangzhou Maternal and Child Health Hospital, Yangzhou, China Ziheng Wang Department of Children Rehabilitation, Yangzhou Maternal and Child Health Hospital, Yangzhou, China Minhua Chen Developmental Behavioural Child Health unit, Affiliated Hospital of Yangzhou University, Yangzhou, China Kelong Cai Sports Psychology Laboratory of College of Physical Education, Yangzhou University, Yangzhou, China Kang Yang Department of Rehabilitation Medicine, Northern Jiangsu People's Hospital, Yangzhou, China https://orcid.org/0000-0002-8669-3105 DOI: https://doi.org/10.47391/JPMA.30406 Keywords: LMNA-related congenital muscular dystrophy, genetic deficiency, therapeutic rehabilitation, motor function Abstract Lamin A/C (LMNA)-associated congenital muscular dystrophy (L-CMD) is a rare neuromuscular disorder caused by mutations in the LMNA gene, characterised by droopy head syndrome with motor developmental delays and weakness of the spinal axial and proximal muscles of the extremities. This case report describes the 10-year therapeutic rehabilitation and follow-up of an 18-month-old girl whose parents complained of slender neck and muscle weakness at the Rehabilitation Medicine Department, Northern Jiangsu People’s Hospital, Yangzhou, China. The purpose of this case report is to demonstrate that early, continuous, and systematic motor rehabilitation training proved to be conducive to the development of motor function in this L-CMD child. Keywords: LMNA-related congenital muscular dystrophy, Genetic deficiency, Therapeutic rehabilitation, Motor function. Downloads Full Text Article Published 2026-06-25 How to Cite Liu, Z., Zhao, S., Wang, Z., Chen, M., Cai, K., & Yang, K. (2026). A 10-year follow-up of therapeutic rehabilitation in a child with LMNA-associated congenital muscular dystrophy: a case report. Journal of the Pakistan Medical Association, 76(07), 1166–1170. https://doi.org/10.47391/JPMA.30406 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 76 No. 07 (2026): JULY Section CASE REPORT License Copyright (c) 2026 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.