Splenic infarct: a rare complication in extensively drug-resistant Salmonella typhi Authors Arfa Fatima Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan Fatimah Sireen Yousuf Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan Muhammad Arbaz Arshad Khan Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan Ainan Arshad Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan DOI: https://doi.org/10.47391/JPMA.30121 Keywords: Enteric fever, Splenic infarct, XDR Salmonella typhi Abstract Enteric fever is a common systemic infection characterised by high grade fever and variable gastrointestinal symptoms. Splenic abscesses, thrombosis, and infarcts are uncommon complications. We report a case of splenic infarction in a young female presenting with persistent fever and abdominal pain. Her blood culture showed drug-resistant Salmonella Typhi (S.Typhi). Due to persistent abdominal pain, abdominal imaging was performed, which revealed multiple splenic infarcts. Treatment with appropriate antibiotics led to complete resolution of symptoms. This case emphasises the importance of timely diagnosis with relevant investigations for the effective management of an unusual presentation of enteric fever. Keywords: Enteric fever, splenic infarct, XDR Salmonella typhi. Downloads Full Text Article Published 2026-05-28 How to Cite Fatima, A., Yousuf, F. S., Khan, M. A. A., & Arshad, A. (2026). Splenic infarct: a rare complication in extensively drug-resistant Salmonella typhi. Journal of the Pakistan Medical Association, 76(06), 954–956. https://doi.org/10.47391/JPMA.30121 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 76 No. 06 (2026): JUNE Section CASE REPORT License Copyright (c) 2026 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.