Hyperostosis Frontalis Simulating Metastatic Deposits: Unmasked on SPECT-CT Authors Areeba Amin Department of Nuclear Medicine, Shaukat Khanum Memorial Cancer Hospital and Research Center, Lahore. Mairah Razi Department of Nuclear Medicine, Shaukat Khanum Memorial Cancer Hospital and Research Center, Lahore. DOI: https://doi.org/10.47391/JPMA.24-48 Abstract Skeletal scintigraphy has a pivotal role in detecting a number of bone pathologies, but it has its own limitations becauseof 2D image acquisition. Hybrid imaging acts as a savior in these cases where it is difficult to distinguish between benignand malignant lesions just on the basis of planar images. We present one such case of known breast carcinoma withabnormal increased radiotracer uptake in the skull which was difficult to characterize as benign lesion such as hyperostosisfrontalis or metastatic osseous lesion. The importance of describing this case is to have a thorough understanding ofhyperostosis patterns and to not confuse it with metastatic deposits in patients with known malignancies. Keywords: Hyperostosis Frontalis, SPECT-CT, bone scan Downloads Full Text Article Published 2024-05-24 How to Cite Areeba Amin, & Mairah Razi. (2024). Hyperostosis Frontalis Simulating Metastatic Deposits: Unmasked on SPECT-CT. Journal of the Pakistan Medical Association, 74(6), 1197–1198. https://doi.org/10.47391/JPMA.24-48 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 74 No. 6 (2024): JUNE Section IMAGING CORNER License Copyright (c) 2024 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.