Evaluation of c-reactive protein in breast cancer by enzyme linked immunoassay technique Authors Ambreen Usmani Department of Anatomy, Bahria University Medical and Dental College, Karachi, Pakistan Mehreen Lateef Department of Biochemistry, Bahria University Medical and Dental College, Karachi, Pakistan DOI: https://doi.org/10.47391/JPMA.297 Abstract Objective: To explore the serum levels of C-reactive protein in breast cancer patients, and to investigate the relationship between inflammation and progression of breast cancer. Methods: The case-control study was conducted at Bahria University Medical and Dental College, Karachi, from September 2015 to December 2018, and comprised breast cancer patients in group A and and an equal number of age-matched healthy women in control group B. C-reactive protein levels were evaluated in serum samples using enzyme-linked immunosorbent assay in both the groups and micro ribonucleic acid levels in serum were quantified using real time polymerase chain reaction. Data was analysed using SPSS 16. Results: Of the 170 subjects, 85(50%) were in each of the two groups. C-reactive protein and micro ribonucleic acid expression were significantly different in group A (p<0.001). There was no correlation (r = 0.162, p>0.01) between the tumour markers in group B (p>0.05). Conclusion: Significantly raised C-reactive protein levels showed there was a link between inflammation and breast cancer. Key Words: Breast cancer, C-reactive protein, MicroRNA 16. Continuous.... Downloads Full Text Article Published 2020-11-03 How to Cite Ambreen Usmani, & Mehreen Lateef. (2020). Evaluation of c-reactive protein in breast cancer by enzyme linked immunoassay technique. Journal of the Pakistan Medical Association, 71(2), 424–428. https://doi.org/10.47391/JPMA.297 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 71 No. 2 (2021): FEBRUARY "A" Section Research Article