Frequency of French-American-British subtypes of acute myeloid leukaemia in a tertiary care hospital of Karachi Authors Irtiza Ahmed Bhatti Department of Oncology, Jinnah Postgraduate Medical Centre, Karachi, Pakistan Ghulam Haider Department of Oncology, Jinnah Postgraduate Medical Centre, Karachi, Pakistan Youksal Intikhab Khan Fourth Year MBBS Student, Jinnah Sindh Medical University, Karachi, Pakistan Taher Saifuddin Fourth Year MBBS Student, Jinnah Sindh Medical University, Karachi, Pakistan DOI: https://doi.org/10.47391/JPMA.1490 Abstract The aim of this study was to determine the frequency of different subtypes of acute myeloid leukaemia (AML) cases that presented in a tertiary care hospital of Karachi. It was a retrospective cross-sectional study, conducted in the hospital’s Oncology department. Data of patients admitted during 2018 was collected from the records. In this study, patients were included using the non-probable convenient sampling technique. Selected cases were classified according to the French-American-British (FAB) classification and data analysis was performed using the SPSS version 25.0. Among the 61 patients included in the study, 28 were males and 33 were females, with a male to female ratio of 1:1.2. The patients’ age ranged between 15 and 92 years and the mean age of diagnosis was 36.13± 15.5 years. M2 was the most common FAB subtype in 14(29.8%) patients, followed by M1 in 11(23.4%) patients. Myeloperoxidase (MPO) was positive in 44 (71.4%) of those cases. Keywords: Acute myeloid Leukaemia (AML), French-American-British (FAB) classification. Author Biographies Ghulam Haider, Department of Oncology, Jinnah Postgraduate Medical Centre, Karachi, Pakistan Department of Oncology, Associate professor and Head Of Department. Youksal Intikhab Khan, Fourth Year MBBS Student, Jinnah Sindh Medical University, Karachi, Pakistan Fourth-year medical student Taher Saifuddin, Fourth Year MBBS Student, Jinnah Sindh Medical University, Karachi, Pakistan Fourth-year medical student Published 2022-02-03 How to Cite Bhatti, I. A., Haider, G. ., Khan, Y. I., & Saifuddin, T. (2022). Frequency of French-American-British subtypes of acute myeloid leukaemia in a tertiary care hospital of Karachi. Journal of the Pakistan Medical Association, 72(3). https://doi.org/10.47391/JPMA.1490 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 72 No. 3 (2022): MARCH Section ORIGINAL ARTICLE