Frequency of French-American-British subtypes of acute myeloid leukaemia in a tertiary care hospital of Karachi

Authors

  • Irtiza Ahmed Bhatti Department of Oncology, Jinnah Postgraduate Medical Centre, Karachi, Pakistan
  • Ghulam Haider Department of Oncology, Jinnah Postgraduate Medical Centre, Karachi, Pakistan
  • Youksal Intikhab Khan Fourth Year MBBS Student, Jinnah Sindh Medical University, Karachi, Pakistan
  • Taher Saifuddin Fourth Year MBBS Student, Jinnah Sindh Medical University, Karachi, Pakistan

DOI:

https://doi.org/10.47391/JPMA.1490

Abstract

The aim of this study was to determine the frequency of different subtypes of acute myeloid leukaemia (AML) cases that presented in a tertiary care hospital of Karachi. It was a retrospective cross-sectional study, conducted in the hospital’s Oncology department. Data of patients admitted during 2018 was collected from the records. In this study, patients were included using the non-probable convenient sampling technique. Selected cases were classified according to the French-American-British (FAB) classification and data analysis was performed using the SPSS version 25.0. Among the 61 patients included in the study, 28 were males and 33 were females, with a male to female ratio of 1:1.2. The patients’ age ranged between 15 and 92 years and the mean age of diagnosis was 36.13± 15.5 years. M2 was the most common FAB subtype in 14(29.8%) patients, followed by M1 in 11(23.4%) patients. Myeloperoxidase (MPO) was positive in 44 (71.4%) of those cases.

Keywords: Acute myeloid Leukaemia (AML), French-American-British (FAB) classification.

Author Biographies

Ghulam Haider, Department of Oncology, Jinnah Postgraduate Medical Centre, Karachi, Pakistan

Department of Oncology, Associate professor and Head Of Department.

Youksal Intikhab Khan, Fourth Year MBBS Student, Jinnah Sindh Medical University, Karachi, Pakistan

Fourth-year medical student

Taher Saifuddin, Fourth Year MBBS Student, Jinnah Sindh Medical University, Karachi, Pakistan

Fourth-year medical student

Published

2022-02-03

How to Cite

Bhatti, I. A., Haider, G. ., Khan, Y. I., & Saifuddin, T. (2022). Frequency of French-American-British subtypes of acute myeloid leukaemia in a tertiary care hospital of Karachi. Journal of the Pakistan Medical Association, 72(3). https://doi.org/10.47391/JPMA.1490

Issue

Section

ORIGINAL ARTICLE