Incidence of acute kidney injury and assessment of its associated risk factors in patients undergoing transarterial chemoembolisation for hepatocellular carcinoma Authors Kamran Muddasar Saeed KRL Hospital, Islamabad, Pakistan Afifa Aftab University of Sheffield, Sheffield, England Muhammad Abu Bakar Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan Junaid Iqbal Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan DOI: https://doi.org/10.47391/JPMA.1286 Abstract Objectives: To determine the incidence of acute kidney injury in intermediate stage hepatocellular carcinoma patients undergoing trans-arterial chemoembolisation, and to analyse various causative factors. Method: The retrospective study was conducted at the Shaukat Khanum Cancer Memorial Hospital, Lahore, Pakistan,, and comprised data from January 2012 to December 2015 of adult patients of either gender with intermediate stage hepatocellular carcinoma and undergoing trans-arterial chemoembolisation with Child-Pugh score A. Outcomes were measured in the form of development of acute kidney injury, and its causative factors. Data was analysed using SPSS 20. Results: Of the 133 patients, 90(67.6%) were male. The overall mean age of the sample was 59±8.4 years (range: 26-86 years). Of these, 19(14%) developed acute kidney injury. Higher alpha-fetoprotein levels and lower albumin levels were found to be the significant causative factors (p<0.05). Conclusion: The incidence of trans-arterial chemoembolisation-related acute kidney injury was 14%. Higher baseline alpha-fetoprotein and lower baseline albumin levels were found to be the significant risk factors. Key Words: Transarterial chemoembolisation, TACE, Acute Kidney Injury, AKI, Hepatocellular carcinoma, HCC, Risk factors. Downloads Full Text Article Published 2022-01-29 How to Cite Saeed, K. M., Afifa Aftab, Muhammad Abu Bakar, & Junaid Iqbal. (2022). Incidence of acute kidney injury and assessment of its associated risk factors in patients undergoing transarterial chemoembolisation for hepatocellular carcinoma. Journal of the Pakistan Medical Association, 72(6), 1057–1060. https://doi.org/10.47391/JPMA.1286 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 72 No. 6 (2022): June Section Research Article