Unforeseen severity in a case of neonatal cow milk protein allergy: a case report Authors Alizeh Imran Third Year MBBS Student, Ziauddin University, Karachi, Pakistan https://orcid.org/0000-0003-2875-8078 Fatima Mustafa Lakdawala Third Year MBBS Student, Ziauddin University, Karachi, Pakistan https://orcid.org/0000-0002-8428-0083 Shahzaib Khan Department of Paediatrics, Dr. Ziauddin Hospital, Karachi, Pakistan DOI: https://doi.org/10.47391/JPMA.11615 Keywords: Cow milk protein allergy, Metabolic acidosis, Amino-acid based infant formula, Neonatal food allergy, CMPA Abstract Cow milk protein allergy (CMPA) is one of the most common childhood allergies that manifests with a range of digestive symptoms and skin reactions, which usually resolve with age. In this report, we present the case of a one-month-old male who presented with a rare and severe manifestation of neonatal CMPA. The neonate underwent numerous hospital admissions due to a presentation that closely mimicked symptoms of a metabolic disorder and sepsis. Our primary objective is to highlight the significance of systematically considering or excluding a CMPA diagnosis, irrespective of the severity of presentation. This proactive approach may potentially reduce future complications among the affected paediatric population, thereby preventing prolonged hospitalisation and the associated disease burden, as seen in this case. Keywords: Cow milk protein allergy, Metabolic acidosis, Amino-acid based infant formula, Neonatal food allergy, CMPA. Author Biographies Alizeh Imran, Third Year MBBS Student, Ziauddin University, Karachi, Pakistan Third Year MBBS student at Ziauddin Univesity, Karachi, Pakistan. Fatima Mustafa Lakdawala, Third Year MBBS Student, Ziauddin University, Karachi, Pakistan Third Year MBBS student at Ziauddin University, Karachi, Pakistan Shahzaib Khan, Department of Paediatrics, Dr. Ziauddin Hospital, Karachi, Pakistan MBBS, MD, Head of Department of Pediatrics Downloads Full Text Article Published 2024-10-16 How to Cite Imran , A., Lakdawala, F. M., & Khan, S. (2024). Unforeseen severity in a case of neonatal cow milk protein allergy: a case report. Journal of the Pakistan Medical Association, 74(11), 2039–2041. https://doi.org/10.47391/JPMA.11615 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 74 No. 11 (2024): NOVEMBER Section STUDENT'S CORNER CASE REPORT License Copyright (c) 2024 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.