Steroid induced ocular complications in idiopathic nephrotic syndrome: a cross sectional single center study Authors Zunaira Zulfiqar Department of Paediatric Nephrology, Sindh Institute of Urology and Transplantation, Karachi, Pakistan Fatema Lanewala Department of Ophthalmology, Sindh Institute of Urology and Transplantation, Karachi, Pakistan Sabeeta Khatri Department of Paediatric Nephrology, Sindh Institute of Urology and Transplantation, Karachi, Pakistan Irshad Bajeer Department of Paediatric Nephrology, Sindh Institute of Urology and Transplantation, Karachi, Pakistan Madiha Aziz Department of Paediatric Nephrology, Sindh Institute of Urology and Transplantation, Karachi, Pakistan Seema Hashmi Department of Paediatric Nephrology, Sindh Institute of Urology and Transplantation, Karachi, Pakistan DOI: https://doi.org/10.47391/JPMA.10573 Keywords: Nephrotic syndrome, corticosteroids, cataract, Glaucoma, refrective error Abstract Objective: To screen children receiving steroids to identify ocular complications and their prevalence. Method: The cross-sectional study was conducted at the Paediatric Nephrology and Ophthalmology departments of the Sindh Institute of Urology and Transplantation, Karachi, from May to October 2022, and comprised patients who received at least 1500mg cumulative steroid dose for a minimum of 3 months. They were screened for steroid-sensitive or steroid-resistant nephrotic syndrome. Ocular examinations, including visual acuity, intraocular pressure, slit-lamp biomicroscopy, lens examination and fundus evaluation, were performed. Data was analysed using SPSS 22. Results: Of the 124 subjects with mean age 8.15±2.03 years (range: 6-12 years), 64(51.6%) were boys. Steroid-sensitive nephrotic syndrome was present in 97(78%) cases. The mean cumulative steroid dose was 3999.31±1564.22mg. Overall, 36(29%) children developed ocular complications. Blood pressure, number of relapses and the duration of treatment were significantly associated (p<0.05). Conclusion: Refractive errors were the most frequent side effects/complication seen among children with nephrotic syndrome who received prolonged corticosteroids. Key Words: Nephrotic syndrome, Corticosteroids, Cataract, Glaucoma, Refractive error. Downloads Full Text Article Published 2024-01-20 How to Cite Zulfiqar, Z., Fatema Lanewala, Sabeeta Khatri, Irshad Bajeer, Madiha Aziz, & Seema Hashmi. (2024). Steroid induced ocular complications in idiopathic nephrotic syndrome: a cross sectional single center study. Journal of the Pakistan Medical Association, 74(2), 315–319. https://doi.org/10.47391/JPMA.10573 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 74 No. 2 (2024): FEBRUARY Section Research Article License Copyright (c) 2024 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.