Association of latent autoimmune diabetes of adults with type 3 polyglandular autoimmune syndrome—a diagnostic challenge Authors Urooj Lal Rehman Department of Endocrinology, Ali Medical, Islamabad, Pakistan https://orcid.org/0000-0003-4190-0657 Hafiz Muhammad Hamza 4th Year MBBS Student, School of Medicine, Foundation University School of Health Sciences, Islamabad, Pakistan https://orcid.org/0009-0000-9772-9356 Muhammad Muiz Malik 4th Year MBBS Student, Foundation University School of Health Sciences, Islamabad, Pakistan https://orcid.org/0009-0001-0431-5953 Ayaz Ahmed Awan 4th Year MBBS Student, School of Medicine, Foundation University School of Health Sciences, Islamabad, Pakistan DOI: https://doi.org/10.47391/JPMA.10108 Keywords: Hashimoto’s thyroiditis, Type 3 polyglandular syndrome, Diabetes mellitus, Latent autoimmune diabetes, Autoantibodies, Case report Abstract Autoimmune polyendocrine syndromes (APS) encompass multiple endocrine gland insufficiencies associated with autoimmune disease. This case report underscores the importance of recognising the association between latent autoimmune diabetes of adults (LADA) and type 3 polyglandular syndrome. A 42-year-old man belonging to Rawalpindi, Pakistan, presented to the outpatient department (OPD) of Ali Medical Centre, Islamabad, in January 2023 with the complaints of extreme thirst and frequent urination. The patient reported consistently raised appetite and eating four to five meals a day along with abrupt weight loss, dry mouth, fatigue occasional dizziness, and dyspnoea. He was diagnosed with type 3 polyglandular syndrome with association of LADA. Daily administration of 10 units of glargine insulin, along with six units of rapid-acting insulin, was prescribed. The patient's HbA1c level reduced in a few months after successive follow-up. ---Continue Downloads Full Text Article Published 2024-04-22 How to Cite Urooj Lal Rehman, Hafiz Muhammad Hamza, Muhammad Muiz Malik, & Ayaz Ahmed Awan. (2024). Association of latent autoimmune diabetes of adults with type 3 polyglandular autoimmune syndrome—a diagnostic challenge. Journal of the Pakistan Medical Association, 74(5), 990–992. https://doi.org/10.47391/JPMA.10108 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 74 No. 5 (2024): MAY Section CASE REPORT License Copyright (c) 2024 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.