Intracranial metastasis of testicular germ cell tumours Authors Zara Shah Section of Neurosurgery, Department of Surgery, Aga Khan University, Karachi, Pakistan Hafiza Hifza Bashir Liaquat National Hospital and Medical College, Karachi, Pakistan Saqib Kamran Bakhshi Section of Neurosurgery, Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan Muhammad Shahzad Shamim Section of Neurosurgery, Department of Surgery, Aga Khan University Hospital, Karachi DOI: https://doi.org/10.47391/JPMA.23-37 Keywords: Intracranial metastasis of testicular germ cell tumours Abstract Brain metastasis from testicular germ cell tumour (TGCT) is rare and represents only 2% of metastatic brain tumours. Although TGCTs have a good survival rate, the prognosis of brain metastasis is poor. Due to the rarity of the diagnosis, there are limited studies on the topic and a standardized treatment protocol does not exist. Surgical management has long been considered a positive prognostic factor; however, recent studies have investigated the impact of chemotherapy and radiotherapy in these patients. Current literature suggests multiplicity of brain lesions and treatment with chemotherapy or radiotherapy alone can have a poor impact on the prognosis of the disease. However, studies with larger cohorts are required to understand and develop the optimal treatment protocol for patients with brain metastasis from TGCT. Downloads Full Text Article Published 2023-04-15 How to Cite Zara Shah, Hafiza Hifza Bashir, Saqib Kamran Bakhshi, & Muhammad Shahzad Shamim. (2023). Intracranial metastasis of testicular germ cell tumours. Journal of the Pakistan Medical Association, 73(05), 1137–1139. https://doi.org/10.47391/JPMA.23-37 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 73 No. 05 (2023): MAY Section EVIDENCE BASED NEURO-ONCOLOGY License Copyright (c) 2023 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.