Betibeglogene Autotemcel; A new hope for transfusion dependent beta-thalassaemia Authors Hiba Tariq Wally Department of Orthopaedic Surgery, Jinnah Postgraduate Medical Centre, Karachi, Pakistan https://orcid.org/0000-0001-8765-4776 Muhammad Hassan Zulfi Department of Orthopaedic Surgery, Jinnah Postgraduate Medical Centre, Karachi, Pakistan Elahi Sana Jilani Department of Orthopaedic Surgery, Jinnah Postgraduate Medical Centre, Karachi, Pakistan DOI: https://doi.org/10.47391/JPMA.9532 Abstract Respected Editor, Beta thalassaemia is an autosomal recessive disorder that leads to abnormal production of functional adult haemoglobin because of either inadequate or absent production of the B globin chain (beta+/beta0).1 Transfusion-dependent thalassemia (TDT) is a rare and most severe form requiring life-long blood transfusions. To mitigate the effects of TDT, life-long blood transfusions every 2-5 weeks are required, which can elicit transfusion-based reactions and lead to an iron overload state, which can further cause widespread organ damage despite the use of iron chelation therapy.2 Continue... Downloads Full Text Article Published 2023-09-13 How to Cite Wally, H. T., Zulfi, M. H., & Jilani, E. S. (2023). Betibeglogene Autotemcel; A new hope for transfusion dependent beta-thalassaemia. Journal of the Pakistan Medical Association, 73(10), 2129–2130. https://doi.org/10.47391/JPMA.9532 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 73 No. 10 (2023): OCTOBER Section LETTER TO THE EDITOR License Copyright (c) 2023 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.