Evaluation of hypomagnesaemia in diabetic patients with nephropathy in a reference clinical laboratory: a comparative cross sectional study

Authors

  • Sumaiya Qamar Department of Chemical Pathology and Endocrinology, Armed Forces Institute of Pathology, National University of Medical Sciences, Rawalpindi, Pakistan
  • Muhammad Anwar Department of Chemical Pathology and Endocrinology, Armed Forces Institute of Pathology, National University of Medical Sciences, Rawalpindi, Pakistan
  • Zujaja Hina Haroon Department of Chemical Pathology and Endocrinology, Armed Forces Institute of Pathology, National University of Medical Sciences, Rawalpindi, Pakistan
  • Afshan Bibi Department of Chemical Pathology and Endocrinology, Armed Forces Institute of Pathology, National University of Medical Sciences, Rawalpindi, Pakistan
  • Muhammad Usman Munir Department of Chemical Pathology and Endocrinology, Armed Forces Institute of Pathology, National University of Medical Sciences, Rawalpindi, Pakistan
  • Sobia Irum Kirmani Department of Chemical Pathology and Endocrinology, Armed Forces Institute of Pathology, National University of Medical Sciences, Rawalpindi, Pakistan

DOI:

https://doi.org/10.47391/JPMA.6887

Abstract

Serum Magnesium plays a significant role in different diabetic complications. This comparative cross sectional study was conducted to evaluate serum magnesium levels in patients with Type 2 Diabetes Mellitus (T2DM) with and without nephropathy. A total of 182 diabetic patients (91 with nephropathy and 91 without nephropathy) were included. Odds ratio were calculated and Mann Whitney U test was used to compare quantitative variables; p<0.05 was considered significant. The results showed that 64/91 (70.3%) patients with nephropathy had hypomagnesaemia as compared to 21/91 (23.07%) patients without nephropathy. The risk of hypomagnesaemia was higher in patients with nephropathy than without nephropathy (Odds ratio 2.7 vs 0.34). Median magnesium levels (1.73 mg/dl) were lower in patients with nephropathy as compared to patients without nephropathy (2.09 mg/dl), p <0.01. It is concluded that magnesium levels were significantly lower in patients with diabetic nephropathy as compared to without nephropathy.

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Published

2023-03-15

How to Cite

Sumaiya Qamar, Muhammad Anwar, Zujaja Hina Haroon, Afshan Bibi, Muhammad Usman Munir, & Sobia Irum Kirmani. (2023). Evaluation of hypomagnesaemia in diabetic patients with nephropathy in a reference clinical laboratory: a comparative cross sectional study. Journal of the Pakistan Medical Association, 73(4), 869–871. https://doi.org/10.47391/JPMA.6887

Issue

Vol. 73 No. 4 (2023): April

Section

Short Communication

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