Symmetrical peripheral gangrene complicating recurrent cholangiocarcinoma: a case report

Authors

  • Chao Yang Department of Critical Care Medicine, The Second Hospital of Traditional Chinese Medicine of Yibin, Yibin, China
  • Jing Hu Department of Critical Care Medicine, The Second Hospital of Traditional Chinese Medicine of Yibin, Yibin, China
  • Xiaoping He Department of Critical Care Medicine, The Second Hospital of Traditional Chinese Medicine of Yibin, Yibin, China
  • Xianming Fan Department of Respiratory and Critical Care Medicine, The Affiliated Hospital of Southwest Medical University, Luzhou, China

DOI:

https://doi.org/10.47391/JPMA.21093

Keywords:

Cholangiocarcinoma, Symmetrical peripheral gangrene, Sepsis, Diffuse intravascular coagulation

Abstract

Symmetrical peripheral gangrene (SPG) is a rare, life-threatening complication often linked to severe illnesses. This case report describes the case of a 28-year-old male with recurrent cholangiocarcinoma who developed SPG after being admitted to the intensive care unit (ICU) for septic shock. Despite initial survival with antibiotics, vasopressors, and supportive care, he refused amputation, leading to secondary infection and death. Early management of septic shock and disseminated intravascular coagulation (DIC), with cautious vasopressor use, is crucial to prevent SPG.

Keywords: Cholangiocarcinoma, Symmetrical peripheral gangrene, Sepsis, Diffuse intravascular coagulation.

Downloads

Published

2025-07-28

How to Cite

Yang, C., Hu, J., He, X., & Fan, X. (2025). Symmetrical peripheral gangrene complicating recurrent cholangiocarcinoma: a case report. Journal of the Pakistan Medical Association, 75(8), 1277–1280. https://doi.org/10.47391/JPMA.21093

Issue

Vol. 75 No. 8 (2025): AUGUST

Section

CASE REPORT

License

Copyright (c) 2025 Journal of the Pakistan Medical Association

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.