A rare case of Gynura-segetum-related hepatic sinus obstruction syndrome complicated with alcoholic liver disease Authors Yidan Gao The affiliated Hospital of Hangzhou Normal University, China. Xiangbo Zhang The affiliated Hospital of Hangzhou Normal University, China. Xiang Zhou The affiliated Hospital of Hangzhou Normal University, China. Jie Wang The affiliated Hospital of Hangzhou Normal University, China. Ling Gong The affiliated Hospital of Hangzhou Normal University, China. Gongying Chen The affiliated Hospital of Hangzhou Normal University, China DOI: https://doi.org/10.47391/JPMA.9296 Keywords: Gynura segetum, Hepatic sinusoidal obstruction syndrome, Transjugular intrahepatic portosystemic shunt Abstract Hepatic sinus obstruction syndrome (HSOS) is easy to be misdiagnosed or missed, and there is no unified and effective treatment for it. A patient was considered to have Budd-Chiari syndrome. He underwent a transjugular liver biopsy, and pathological examination revealed HSOS without liver cirrhosis. After the failure of anticoagulation therapy, he successfully received a transjugular intrahepatic portosystemic shunt (TIPS). After discharge, he was followed-up for four years with a good prognosis. G. segetum-induced HSOS can be easily overlooked, especially in patients with underlying liver diseases. When medical therapy fails, TIPS can control ascites and portal hypertension, and the long-term prognosis is optimistic. Key words: Gynura segetum; Hepatic sinusoidal obstruction syndrome; Transjugular intrahepatic portosystemic shunt. Downloads Full Text Article Published 2024-06-28 How to Cite Yidan Gao, Xiangbo Zhang, Xiang Zhou, Jie Wang, Ling Gong, & Gongying Chen. (2024). A rare case of Gynura-segetum-related hepatic sinus obstruction syndrome complicated with alcoholic liver disease. Journal of the Pakistan Medical Association, 74(7), 1355–1357. https://doi.org/10.47391/JPMA.9296 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 74 No. 7 (2024): JULY Section CASE REPORT License Copyright (c) 2024 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.