Loeffler’s Endocarditis- A cause of endomyocardial fibrosis in a patient of juvenile idiopathic arthritis: A Case Report Authors Taqdees Khaliq Federal Government Polyclinic Hospital, Islamabad, Pakistan Sarah Azam Shah Federal Government Polyclinic Hospital, Islamabad, Pakistan Saad Saleem Federal Government Polyclinic Hospital, Islamabad, Pakistan Safina Hameed Qureshi Federal Government Polyclinic Hospital, Islamabad, Pakistan Hamid Iqbal Federal Government Polyclinic Hospital, Islamabad, Pakistan Fahad Khalid Federal Government Polyclinic Hospital, Islamabad, Pakistan DOI: https://doi.org/10.47391/JPMA.8648 Keywords: Endomyocardial fibrosis, Juvenile Idiopathic Arthritis (JIA), TNF alpha inhibitors, Hyper-eosinophilic syndrome (HES) Abstract Endomyocardial fibrosis secondary to hyper-eosinophilic syndrome also known as Loeffler’s Endocarditis is a rare cause of restrictive cardiomyopathy. If left untreated, it carries a very high morbidity and mortality rate. The case of a 20 years old girl, a known case of polyarticular juvenile idiopathic arthritis since the age of 13 years was reported at Federal Government Polyclinic Hospital, Islamabad on 14th May 2022. She presented with an acute history of shortness of breath and cough for two weeks. Her initial echocardiogram showed suspicion of Loeffler’s Endocarditis, which is attributed to be an adverse effect of etanercept- a tumour necrosis factor (TNF) inhibitor, which she had been prescribed for her arthritis. The patient is currently being managed with high doses of steroids, therapeutic anticoagulation with rivaroxaban, carvedilol for tachycardia and mycophenolate mofetil as an immunosuppressant. Key Words: Endomyocardial fibrosis, Juvenile Idiopathic Arthritis (JIA), TNF alpha inhibitors, Hyper-eosinophilic syndrome (HES). Author Biographies Sarah Azam Shah, Federal Government Polyclinic Hospital, Islamabad, Pakistan Rheumatology department. write up of the case report and part of the treating team Saad Saleem, Federal Government Polyclinic Hospital, Islamabad, Pakistan Rheumatology Department Part of the treating team, referencing and write up Safina Hameed Qureshi, Federal Government Polyclinic Hospital, Islamabad, Pakistan Rheumatology Department Part of the treating team and Proof Reading. Hamid Iqbal, Federal Government Polyclinic Hospital, Islamabad, Pakistan Physician Cardiology . part of treating team from cardiology side , helped in making the diagnosis. Downloads Full Text Article Published 2024-03-20 How to Cite Khaliq, T., Shah, S. A., Saleem, D. S. S., Qureshi, S. H., Iqbal, D. H. I., & Khalid, D. F. K. (2024). Loeffler’s Endocarditis- A cause of endomyocardial fibrosis in a patient of juvenile idiopathic arthritis: A Case Report. Journal of the Pakistan Medical Association, 74(4), 788–790. https://doi.org/10.47391/JPMA.8648 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 74 No. 4 (2024): APRIL Section CASE REPORT License Copyright (c) 2024 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.