Association of serotonin levels in patients of vasovagal syncope and postural tachycardia syndrome Authors Hammad Raziq Department of Physiology, Multan Medical and Dental college, Multan, Pakistan Humaira Fayyaz Department of Physiology, Islamic International Medical College, Rawalpindi, Pakistan Rabia Azhar Department of Physiology, Islamic International Medical College, Rawalpindi, Pakistan Azmat Hayyat Department of Electrophysiology, Armed Forces Institute of Cardiology, Rawalpindi, Pakistan Sobia Waqas Department of Physiology, Islamic International Medical College, Rawalpindi, Pakistan DOI: https://doi.org/10.47391/JPMA.053 Abstract Abstract Objective: To determine the level of serotonin in patients of vasovagal syncope and postural tachycardia syndrome after head-up tilt test. Method: The cross-sectional analytical study was conducted at the Islamic International Medical College and the Department of Electrophysiology, Armed Forces Institute of Cardiology, Rawalpindi, from April 2017 to March 2018. Group A comprised cases of vasovagal syncope, group B had patients of postural tachycardia syndrome, and group C had healthy controls. Cases were chosen on the basis of history, episodes of syncope and findings of head-up tilt test. After the test, blood samples were taken for hormonal analysis of serotonin using enzyme-linked immunosorbent assay. Data was analysed using SPSS 21. Results: Of the 80 subjects, 35(43.8%) were in group A, 35(43.8%) in group B and 10(12.4%) in group C. Mean serotonin value in group A was 918.39±380.16nM, in group B it was 1188.70±449.55nM., while in control group C the mean value was 771.40±376.14nM (p<0.05) Conclusion: Serotonin was found to have a significant role in syncope pathophysiology. Continuous... Additional Files PDF Published 2021-04-19 How to Cite Hammad Raziq, Humaira Fayyaz, Rabia Azhar, Azmat Hayyat, & Sobia Waqas. (2021). Association of serotonin levels in patients of vasovagal syncope and postural tachycardia syndrome. Journal of the Pakistan Medical Association, 1–10. https://doi.org/10.47391/JPMA.053 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue A Head of Print Section Research Article