Herbal extracts: the future treatment option for drug-resistant epilepsy

Authors

  • Mehr Musani Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan
  • Muhammad Wasim Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan
  • Hassan Salman Siddiqi Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan
  • Saara Muddasir Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan
  • Fazal Manzoor Arain Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan

DOI:

https://doi.org/10.47391/JPMA.7081

Keywords:

Epilepsy, Herbal extracts, Drug-resistant epilepsy, Anti-epileptic drugs

Abstract

Epilepsy is a neurological disorder characterised by two or more unprovoked seizures. The high prevalence and incidence of epilepsy globally, especially in Asia, has remained a big concern over the course of centuries. Patients are usually prescribed the already known anti-epileptic drugs, but even after going through three different generations of anti-epileptic drugs, some people still suffer from drug-resistant form of epilepsy. These patients are usually prescribed a higher dose of anti-epileptic drugs, which results in more adverse effects. That is why new treatment options, like herbal extracts, should be explored for patients who do not respond to the classic anti-epileptic drugs. The current narrative review was planned to explore if herbal extracts can be the future for the treatment of drug-resistant epilepsy.

Key Words: Epilepsy, Herbal extracts, Drug-resistant epilepsy, Anti-epileptic drugs.

Author Biographies

Mehr Musani, Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan

MPhil Student,

Department of Biological and Biomedical Sciences

Aga Khan University

Karachi, Pakistan

Muhammad Wasim, Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan

PostDoctral Fellow,

Department of Biological and Biomedical Sciences

Aga Khan University

Karachi, Pakistan

Hassan Salman Siddiqi, Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan

Assistant Professor

Department of Biological and Biomedical Sciences

Aga Khan University

Karachi, Pakistan

Saara Muddasir, Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan

Assistant Professor

Department of Biological and Biomedical Sciences

Aga Khan University

Karachi, Pakistan

Fazal Manzoor Arain, Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan

Assistant Professor

Department of Biological and Biomedical Sciences

Aga Khan University

Karachi, Pakistan

Published

2023-05-15

How to Cite

Mehr Musani, Muhammad Wasim, Hassan Salman Siddiqi, Saara Muddasir, & Fazal Manzoor Arain. (2023). Herbal extracts: the future treatment option for drug-resistant epilepsy. Journal of the Pakistan Medical Association, 73(6), 1266–1271. https://doi.org/10.47391/JPMA.7081

Issue

Section

NARRATIVE REVIEW