Basaloid follicular hamartoma syndrome: acquired sporadic variant with hypothyroidism, hypohidrosis and alopecia, a rare case

Authors

  • Ushna Ashraf Department of Dermatology, PNS Shifa Hospital, Karachi, Pakistan
  • Najia Ahmed Department of Dermatology, PNS Shifa Hospital, Karachi, Pakistan
  • Nighat Jamal Department of Histopathology, PNS Shifa Hospital, Karachi, Pakistan
  • Rabia Ahmed Department of Histopathology, PNS Shifa Hospital, Karachi, Pakistan

DOI:

https://doi.org/10.47391/JPMA.6560

Keywords:

Basaloid follicular hamartoma, benign neoplasm, basal cell carcinoma, rare disease, nevoid basal cell carcinoma syndrome

Abstract

Basaloid follicular hamartoma is a rare benign malformation of hair follicles, characterised clinically as generalised or localised multiple brown papules mostly on face, scalp and trunk. It may be congenital or acquired with or without any associated disease. Histologically it is composed of epithelial proliferation of basaloid cells with radial disposition enclosed in a fibrous stroma. It is of important consideration because it can be mistaken for basal cell carcinoma both clinically and histologically. Here we report the case of a 51-year-old female with acquired, generalised basaloid follicular hamartomas associated with alopecia, hypothyroidism and hypohidrosis which is an extremely rare disease.

Key Words: Basaloid follicular hamartoma, benign neoplasm, basal cell carcinoma, rare disease, nevoid basal cell carcinoma syndrome.

Author Biographies

Ushna Ashraf, Department of Dermatology, PNS Shifa Hospital, Karachi, Pakistan

Resident Dermatologist
Department of Dermatology

Najia Ahmed, Department of Dermatology, PNS Shifa Hospital, Karachi, Pakistan

Associate Professor
Classified Dermatologist
Dermatology Department

Nighat Jamal, Department of Histopathology, PNS Shifa Hospital, Karachi, Pakistan

Associate Professor.

Consultant Histopathologist

Rabia Ahmed, Department of Histopathology, PNS Shifa Hospital, Karachi, Pakistan

Consultant Histopathologist

Assistant Professor of Pathology

Published

2023-05-15

How to Cite

Ashraf, U., Ahmed, N., Jamal, N., & Ahmed, R. (2023). Basaloid follicular hamartoma syndrome: acquired sporadic variant with hypothyroidism, hypohidrosis and alopecia, a rare case. Journal of the Pakistan Medical Association, 73(6), 1308–1310. https://doi.org/10.47391/JPMA.6560

Issue

Section

CASE REPORT