Seroprevalence of HBV, HCV, HIV, syphilis, and malaria among blood donors at tertiary care hospital blood bank Authors Hira Qadir Department of Pathology, Dow University of Health Sciences, Karachi, Pakistan Nadia Nasir Department of Haematology, Jinnah Post Graduate Medical Center, Karachi, Pakistan Shaheen Kouser Department of Pathology, Dow University of Health Sciences, Karachi, Pakistan Huma Mansoori Department of Pathology, Dow University of Health Sciences, Karachi, Pakistan Nida Qadir Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan Rozina Baig Department of Pathology, Dow University of Health Sciences, Karachi, Pakistan Areesha Qadir Dow University of Health Sciences, Karachi, Pakistan DOI: https://doi.org/10.47391/JPMA.1344 Abstract Abstract Objective:To ascertain the frequency of markers of transfusion-transmitted infections. among blood donors in a blood bank at a tertiary care hospital Material and Methods:The study was a retrospective cross-sectional descriptive study, covering from 1stJanuary 2013- October 2018 and was conducted in the blood bank section, in the Department of Pathology at Dow University of HealthSciences, Hospital. All blood donors were screened for hepatitis B, hepatitis C, HIV (I & II), syphilis through electrochemiluminescence and malaria (immunochromatography).Data was entered and subsequently analyzed by statistical package for social sciences (SPSS) version 21. The frequency of infectious disease markers (HbsAg, Anti HCV, HIV, syphilis, and malaria) was calculated among blood donors. Results:The total number of donors in our study was 29732, out of which 2587 donors were positive for an infectious disease.Out of the total donors, 29712 were male and 20 were female. There were 12 volunteer donors and 29720 exchange donors. The mean prevalence of donors with positive infectious markers was as follows; Anti HCV was 3 %, HbsAg was 2.9%, Syphilis was 2.0%, HIV was 0.5% and Malaria was 0.02 %. Conclusion:HbsAg and Anti HCV were the most frequent infections (3%) found in our blood donors, followed by syphilis with a frequency of 2%. Keywords: Blood transfusion, transfusion-transmitted infections, blood donors. Downloads Full Text Article Published 2020-11-19 How to Cite Hira Qadir, Nadia Nasir, Shaheen Kouser, Huma Mansoori, Nida Qadir, Rozina Baig, & Areesha Qadir. (2020). Seroprevalence of HBV, HCV, HIV, syphilis, and malaria among blood donors at tertiary care hospital blood bank. Journal of the Pakistan Medical Association, 71(3), 1–9. https://doi.org/10.47391/JPMA.1344 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 71 No. 3 (2021): MARCH Section RESEARCH ARTICLE