The study of frequency of malignancy and its types in surgical jaundice; a tertiary care experience Authors Jamal Anwar Department of Surgery, King Edward Medical University, Mayo Hospital, Lahore, Pakistan Usama Shabbir Department of Surgery, King Edward Medical University, Mayo Hospital, Lahore, Pakistan Mohammad Sohail Asghar Department of Surgery, King Edward Medical University, Mayo Hospital, Lahore, Pakistan https://orcid.org/0000-0002-3516-3104 Hafiz Syed Zaigham Ali Shah Department of Surgery, King Edward Medical University, Mayo Hospital, Lahore, Pakistan Ameer Afzal Department of Surgery, King Edward Medical University, Mayo Hospital, Lahore, Pakistan khalid Masud Gondal Department of Surgery, King Edward Medical University, Mayo Hospital, Lahore, Pakistan DOI: https://doi.org/10.47391/JPMA.3454 Abstract Objective: To determine the frequency of malignancy and its types in patients presenting with surgical jaundice in a tertiary care setting. Method: The cross-sectional study was conducted at the North Surgical Ward, Mayo Hospital, Lahore, Pakistan, from May 8 to November 8, 2020, and comprised patients of either gender with a diagnosis of surgical jaundice made on the basis of history, clinical examination, haematological and biochemical reports and radiological investigations. All patients were managed as per the guidelines for surgical jaundice with injection vitamin K intramuscular, hydration with intravenous fluids, avoidance of constipation by lactulose or neomycin, vitals and urine output monitoring and prophylactic antibiotics. Demographic data as well frequency of malignancy were noted using a predesigned proforma. Data was analysed using SPSS 21. Results: Of the 95 patients, 51(53.7%) were male and 44(46.3%) were female. The overall mean age was 49.96±16.54 years (range: 18-80 years). A total of 19(20%) cases had body mass index <30. Malignancy was identified in 50(52.6%) cases; 14(28%) gallbladder, 4(8%) head of pancreas, 9(18%) peri-ampullary carcinoma, 7(14%) cholangiocarcinoma, 6(12%) Klastkin tumour, 5(10%) hepatocellular carcinoma, and 5(10%) metastatic tumour. Conclusion: More than half of the surgical jaundice cases had malignancy, gallbladder being the most affected site. Key Words: Surgical jaundice, FNAC, Peri-ampullary carcinoma, Klastkin tumour, Hepatocellular carcinoma. Author Biographies Jamal Anwar, Department of Surgery, King Edward Medical University, Mayo Hospital, Lahore, Pakistan Senior Registrar General Surgery North Surgery Department King Edward Medical University Mayo Hospital Lahore Usama Shabbir, Department of Surgery, King Edward Medical University, Mayo Hospital, Lahore, Pakistan Senior Registrar General Surgery North Surgery Department King Edward Medical University Mayo Hospital Lahore Mohammad Sohail Asghar, Department of Surgery, King Edward Medical University, Mayo Hospital, Lahore, Pakistan Post Graduate Resident FCPS General Surgery North Surgery Department King Edward Medical University Mayo Hospital Lahore Hafiz Syed Zaigham Ali Shah, Department of Surgery, King Edward Medical University, Mayo Hospital, Lahore, Pakistan Senior Registrar General Surgery North Surgery Department King Edward Medical University Mayo Hospital Lahore Ameer Afzal, Department of Surgery, King Edward Medical University, Mayo Hospital, Lahore, Pakistan Professor of Surgery North Surgery Department King Edward Medical University Mayo Hospital Lahore khalid Masud Gondal, Department of Surgery, King Edward Medical University, Mayo Hospital, Lahore, Pakistan Professor of Surgery North Surgery Department King Edward Medical University Mayo Hospital Lahore Downloads Full Text Article Published 2022-12-15 How to Cite Anwar, J., Shabbir, U., Mohammad Sohail Asghar, Hafiz Syed Zaigham Ali Shah, Afzal, A., & khalid Masud Gondal. (2022). The study of frequency of malignancy and its types in surgical jaundice; a tertiary care experience. Journal of the Pakistan Medical Association, 73(1), 9–12. https://doi.org/10.47391/JPMA.3454 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 73 No. 1 (2023): JANUARY Section RESEARCH ARTICLE