Renal Barocrinology: The Interface between Obesity and Kidney Health

Authors

  • Sourabh Sharma Department of Nephrology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India;
  • Sabine Karam Division of Nephrology and Hypertension, University of Minnesota, Minneapolis, Minnesota, USA;
  • Nitin Kapoor Department of Endocrinology, Diabetes and Metabolism, Christian Medical College, Vellore, India; Non communicable disease unit, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia;
  • Sanjay Kalra Department of Endocrinology, Bharti Hospital, Karnal, India; University Centre for Research & Development, Chandigarh University, Mohali, India.

DOI:

https://doi.org/10.47391/JPMA.25-56

Abstract

Obesity is been acknowledged to be a major risk factor for
chronic kidney disease (CKD), contributing to both its onset
and progression. Over past few decades, the obesity
epidemic has lead to an increased incidence of obesityrelated
nephropathy, characterised by glomerular
hyperfiltration, hypertrophy, and progressive
glomerulosclerosis. This review highlights the need for
multidisciplinary action to prevent and manage obesityrelated
nephropathy. We reiterate the current necessity of
routine kidney function screening in people with obesity.
We also propose an integrated concept of Renal
Barocrinology. This will focus on early screening and
preventive strategies, mitigating long-term burden of CKD
and its complications, and improving patient outcomes
through a collaborative approach.

Keywords: Obesity, Chronic Kidney Disease,
Hyperfiltration, Proteinuria, Early Screening, Renal
Barocrinology

Published

2025-07-01

How to Cite

Sourabh Sharma, Sabine Karam, Nitin Kapoor, & Sanjay Kalra. (2025). Renal Barocrinology: The Interface between Obesity and Kidney Health. Journal of the Pakistan Medical Association, 75(07), 1145–1147. https://doi.org/10.47391/JPMA.25-56

Issue

Section

ADVANCES IN NEPHROLOGY