Molecular imaging with 68Ga-PSMA PET/CT in high grade glioma: A biomarker for tumour neo-angiogenesis Authors Sharjeel Usmani Department of Radiology and Nuclear Medicine1, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), Muscat Oman; Hull York Medical School, Hull, UK; Khulood Al Riyami Department of Radiology and Nuclear Medicine1, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), Muscat Oman; Shah P Numani Department of Radiology, Carl T Hayden VA Medical Center, Phoenix USA; Syed Furqan Hashmi Department of Radiology and Nuclear Medicine1, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), Muscat Oman; Anjali Jain Department of Radiology and Nuclear Medicine1, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), Muscat Oman; Rashid al Sukaiti Department of Radiology and Nuclear Medicine1, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), Muscat Oman; Najeeb Ahmed Hull York Medical School, Hull, UK; Muhammad Shahzad Shamim Department of Surgery, Aga Khan University Hospital, Karachi Pakistan. DOI: https://doi.org/10.47391/JPMA.24-64 Abstract There are several promising radiotracers used for bothstaging and restaging of primary and recurrent braintumours based on various mechanisms of tracerlocalization in tumour cells. 68Ga-PSMA PET has extremelylow background uptake in normal brain tissue andconsequently high tumour-to-brain ratio making it apromising imaging radiotracer for gliomas. 68Ga-PSMAdemonstrates utility in evaluating high grade gliomaduring both initial workup or when suspecting recurrence.Herein the authors evaluate the role of this imagingmodality and the potential future it holds in themanagement of high grade gliomas.Keywords: 68Ga-PSMA; PET/CT; brain tumors; PET/CT;gliomas; Glioblastoma Multiforme Downloads Full Text Article Published 2024-07-25 How to Cite Sharjeel Usmani, Khulood Al Riyami, Shah P Numani, Syed Furqan Hashmi, Anjali Jain, Rashid al Sukaiti, Najeeb Ahmed, & Muhammad Shahzad Shamim. (2024). Molecular imaging with 68Ga-PSMA PET/CT in high grade glioma: A biomarker for tumour neo-angiogenesis. Journal of the Pakistan Medical Association, 74(8), 1552–1554. https://doi.org/10.47391/JPMA.24-64 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 74 No. 8 (2024): AUGUST Section EVIDENCE BASED NEURO-ONCOLOGY License Copyright (c) 2024 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.