Consensus guidelines for the management of posterior fossa tumour for low- and middle-income countries

Authors

  • Hafiza Fatima Aziz Department of Neurosurgery, The Aga Khan University, Karachi, Pakistan.
  • Mohammad Hamza Bajwa Department of Neurosurgery, The Aga Khan University, Karachi, Pakistan.
  • Naureen Mushtaq 3Department of Paediatric Oncology, The Aga Khan University, Karachi, Pakistan
  • Saqib Kamran Bakhshi Department of Neurosurgery, The Aga Khan University, Karachi, Pakistan.
  • Kaynat Siddiqui Department of Neurosurgery, The Aga Khan University, Karachi, Pakistan.
  • Saad Akhtar Khan Department of Neurosurgery, The Aga Khan University, Karachi, Pakistan.
  • Rabeet Tariq Jumma Research Laboratories, The Aga Khan University, Karachi, Pakistan
  • Muhammad Shakir Jumma Research Laboratories, The Aga Khan University, Karachi, Pakistan.
  • Mehar Masroor Department of Neurosurgery, The Aga Khan University, Karachi, Pakistan.
  • Fatima Suleman Department of Neurosurgery, The Aga Khan University, Karachi, Pakistan.
  • Pakistan Brain Tumour Consortium: (Authors list at the end of the supplement) +92 (021) 32226443
  • Syed Ather Enam Department of Neurosurgery, The Aga Khan University, Karachi, Pakistan.

DOI:

https://doi.org/10.47391/JPMA.S3.GNO-22

Abstract

The posterior fossa is a limited compartment therefore
lesions compressing its structures can result in
devastating outcomes. It can cause significant
neurological deficit due to mass effect on critical
structures and hydrocephalus. Due to the nature of the
infratentorial region, urgent surgical intervention is often
the first-line option. Surgical neuro-oncologists guide
patients and caregivers through the course of this disease
and to inform them about the various options for
management and long-term outcome optimisation.
There is currently conflicting data; however, institutional
experiences can guide us towards achieving
improvements in surgical outcomes and quality of life.
Advances in molecular classifications coupled with highdose
radiation treatment improve our capacity for
improving overall survival in these patients. Common
childhood tumours are ependymomas,
medulloblastomas, and juvenile pilocytic astrocytomas,
while adults often present with metastases, and less
commonly, cerebellar haemangioblastomas and gliomas.
This paper outlines management strategies with
consideration for multidisciplinary care and resourcelimited
settings.
Keywords: Cerebellar neoplasms, medulloblastoma,
caregivers, hemangioblastoma, astrocytoma,
ependymoma, hydrocephalus, neuro-oncology,
neurosurgery, brain tumour, posterior fossa.

Published

2024-06-09

How to Cite

Hafiza Fatima Aziz, Mohammad Hamza Bajwa, Naureen Mushtaq, Saqib Kamran Bakhshi, Kaynat Siddiqui, Saad Akhtar Khan, Rabeet Tariq, Muhammad Shakir, Mehar Masroor, Fatima Suleman, Pakistan Brain Tumour Consortium: (Authors list at the end of the supplement), & Syed Ather Enam. (2024). Consensus guidelines for the management of posterior fossa tumour for low- and middle-income countries. Journal of the Pakistan Medical Association, 74(3 (Supple), S186-S190. https://doi.org/10.47391/JPMA.S3.GNO-22

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