A case report of synchronous bilateral tonsillar carcinoma associated with human papilloma virus Authors Shunji Tamagawa Department of Otolaryngology Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan Mehmet Gunduz Department of Otolaryngology Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan Keisuke Enomoto Department of Otolaryngology Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan Esra Gunduz Department of Otolaryngology Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan Kenji Warigaya Department of Human Pathology, Wakayama Medical University, Wakayama, Japan Muneki Hotomi Department of Otolaryngology Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan DOI: https://doi.org/10.47391/JPMA.721 Abstract The case of a 69-year-old man with bilateral synchronous tonsillar carcinoma is reported. The patient complained of nasal closure, strange voice, and discomfort in his pharynx when he was admitted to the Department of Otolaryngology Head and Neck Surgery at Wakayama Medical University, Wakayama, Japan, in March 2017. The palatine tonsils were enlarged and the surface was irregular. Left cervical lymphadenopathy was also evident. Histological examination from both tonsils was performed and bilateral tonsillar squamous cell carcinoma was diagnosed. PCR analysis showed the same HPV-DNA pattern from bilateral tonsils. Concurrent chemoradiotherapy was performed. Total 70 Gy of irradiation (2Gy/day×35 day) was applied to bilateral tonsillar tumours and upper neck. Follow up was conducted every three months and the patient was free of recurrence for three years. Patient’s informed consent was taken to publish the case report. Keywords: bilateral synchronous tonsillar carcinoma, HPV, tonsil Continuous... Downloads Full Text Article Published 2020-10-24 How to Cite Shunji Tamagawa, Mehmet Gunduz, Keisuke Enomoto, Esra Gunduz, Kenji Warigaya, & Muneki Hotomi. (2020). A case report of synchronous bilateral tonsillar carcinoma associated with human papilloma virus. Journal of the Pakistan Medical Association, 71(1), 352–355. https://doi.org/10.47391/JPMA.721 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 71 No. 1 (2021): JANUARY "B" Section Case Report License Copyright (c) 2020 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.