Deep brain stimulation for Parkinson’s disease in Pakistan: current status, opportunities and challenges Authors Nabeel Muzaffar Syed Department of Neurological Sciences, University of Nebraska Medical Center, Omaha, Nebraska, USA John Bertoni Department of Neurological Sciences, University of Nebraska Medical Center, Omaha, Nebraska, USA Danish Ejaz Bhatti Department of Neurological Sciences, University of Nebraska Medical Center, Omaha, Nebraska, USA DOI: https://doi.org/10.47391/JPMA.879 Abstract Abstract Parkinson’s disease is a slowly progressive neurodegenerative disease that commonly affects people aged 60 years and above. So far, no treatment has been shown to halt or slow the progression of the disease and our options are limited to symptomatic management. Levodopa is the most preferred antiparkinsonian medication that provides excellent control of symptoms early in the disease. However, in most patients the response declines over time and complications of motor fluctuations and dyskinesia arise. Other medical therapies play an adjunctive role in the management, as they are not as effective as levodopa. Advanced therapies like deep brain stimulation (DBS) can provide effective control of symptoms in moderate to advanced disease. Deep brain stimulation surgery has recently been started in Pakistan. This review provides an overview of deep brain stimulation, its indications, patient selection process and details of surgery, Continuous...... Additional Files PDF Published 2020-10-05 How to Cite Nabeel Muzaffar Syed, John Bertoni, & Danish Ejaz Bhatti. (2020). Deep brain stimulation for Parkinson’s disease in Pakistan: current status, opportunities and challenges. Journal of the Pakistan Medical Association, 1–18. https://doi.org/10.47391/JPMA.879 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue A Head of Print Section Special Communication