Evaluation of surgical outcomes of nephron-sparing surgery in a leading hospital of an advanced nation Authors Nadeem Bin Nusrat Department of Urology, University Hospital Galway, Galway, Ireland Kilian Walsh Department of Urology, University Hospital Galway, Galway, Ireland Frank Darcy Department of Urology, University Hospital Galway, Galway, Ireland Garrett Durkan Department of Urology, University Hospital Galway, Galway, Ireland Asadullah Aslam Department of Urology, Letterkenny University Hospital, Donegal, Ireland Saira Imtiaz Pakistan Kidney and Liver Institute and Research Center, Lahore, Pakistan DOI: https://doi.org/10.47391/JPMA.11367 Keywords: Nephron Sparing Surgery, Partial nephrectomy, Small renal masses, Renal score, Perioperative outcomes Abstract Objectives: To assess the efficacy of renal score grading in guiding therapy decisions, predicting perioperative outcomes, and characterising tumours following partial nephrectomy. Methods: The retrospective, single-centre study was conducted at the University College Hospital Galway, Ireland, and comprised data from January 11, 2012, to June 17, 2016, of all patients aged >18 years who underwent partial nephrectomy as part of treatment for kidney cancer. Data was analysed using SPSS 20. Results: Of the 76 patients, 52(68.4%) were males and 24(31.6%) were females. The median age of patients was 58 years (IQR: 16). Tumours were predominantly on the right side 44(57.9%) and lower pole 36(47.4%), with a median tumour size of 2.35 cm (IQR: 1.0 cm), and renal score had a median of 5.00 (IQR: 2). Of the total, 70(92.1%) patients underwent open surgery, with complications in 6(7.9%), which were associated significantly with higher body mass index, American Society of Anaesthesiologists classification score, warm ischemia time and tumour size (p<0.05). Recurrence correlated with tumour size and positive margins (p<0.05). Survival analysis showed a median disease-free survival (DFS) of 30 months (IQR: 6 months). However, due to the absence of events, the median overall survival (OS) and survival estimates could not be fully calculated. The longest follow-up time was 36 months, with no recorded mortality in the cohort. Conclusion: For individuals with comparatively small localised renal tumours, the selection of partial nephrectomy was found to be a suitable alternative, showcasing exceptional results regarding the complication profile, recurrence-free survival and overall survival. Key Words: Nephron Sparing surgery, Partial nephrectomy, Small renal masses, Renal score, Perioperative outcomes. Downloads Full Text Article Published 2024-12-23 How to Cite Nusrat, N. B., Walsh, K., Frank Darcy, Garrett Durkan, Asadullah Aslam, & Imtiaz, S. (2024). Evaluation of surgical outcomes of nephron-sparing surgery in a leading hospital of an advanced nation. Journal of the Pakistan Medical Association, 75(1), 56–60. https://doi.org/10.47391/JPMA.11367 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 75 No. 1 (2025): JANUARY Section RESEARCH ARTICLE License Copyright (c) 2024 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.