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July 2021, Volume 71, Issue 7

Student's Corner

Rolling out COVID-19 vaccine: Half the battle won

Alishba Adnan  ( 3rd Year MBBS Student, Karachi Medical and Dental College, Karachi, Pakistan. )
Chanchal Maheshwari  ( 3rd Year MBBS Student, Karachi Medical and Dental College, Karachi, Pakistan. )
Syed Muhammad Ashraf Jahangeer  ( Department of Community Medicine, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan. )



Madam, in terms of bringing life to still and causing a havoc in the World's economy COVID19 is an unprecedented pandemic in known human history. According to the World Bank forecast COVID19 economic consequences have been estimated as the deepest recession since the Second World War.1,2 To date COVID19 has claimed 1.4 million lives, leaving millions in varying levels of morbidity and emerges as a bigger problem in the high income than in the low middle income countries.3 The only hope to put a stop to this monster and go back to the normal is the man's old friend, the vaccines.4 Extraordinary circumstances require extraordinary measures and we have seen that the development of vaccines which was usually thought as a years of business is being prepared and ready to be rolled out under ten months of concentric efforts.5 It is a really commendable effort of those who put everything into COVID19 vaccine development but there are still concerns about its safety and efficacy and conspiracy theories.6-8 A certain percentage of adverse effects are expected from any medication and the same is true for vaccines.9 However even within the expected numbers of any untoward effects from vaccines, the same are highlighted and become under media limelight for no scientific reason.10 A proactive approach by the relevant authorities to take mass media into confidence on the COVID19 vaccine subject seems inevitable to manage the public response towards vaccines. In the recent history of infections and vaccines, the world has seen both causal and spurious adverse relationships claimed to be associated with vaccines. Whatever the truth was, news of vaccines causing adverse reactions can not only affect the uptake of the very vaccine itself, but can also avert people to go for other routine vaccinations.11 In the low and middle income countries of the world this could prove as an impending community health disaster. In a country like the UK the Wakefield reports caused decline in the vaccine uptake and a surge in the infections, so what worse can be expected in other parts of the world.12 Considering the tight rope of a newly developed vaccine administration in the first stage, 'the first few thousands' in the population would be a make or break situation, specially in the low middle income countries where rumours spread faster than anything. In the second stage, targeting a bigger population for vaccine delivery, diligent planning at both macro and micro levels would be required to avoid problems related to vaccine storage, safe delivery, administration and follow up of the vaccine receivers. This pandemic provided us with an opportunity to uncover our potential in a time constraint Global health crisis. The precious achievements of scientists and vaccine manufacturers in this regard must be capitalized upon and be secured from mishaps and mismanagement.


Disclaimer: None

Conflict of Interest: None

Funding Sources: None




1.      World Bank. 2020. Global Economic Prospects, June 2020. Washington, DC: World Bank. DOI: 10.1596/978-1-4648-1 553-9. License: Creative Commons Attribution CC BY 3.0 IGO accessed from 10986/33748/978146481553 9.pdf

2.      The World Bank press release. COVID-19 to Plunge Global Economy into Worst Recession since World War II 08/covid-19-toplungeglobal-economy-into-worst-recession-since-world-war-ii

3.      World Health Organization. WHO Coronavirus Disease (COVID-19) Dashboard. Data last updated: 2020/11/25, 7:03pm CET. f2-r_cDWbF2H-JPc1Kam5BnorYUWKM07iF xoCObwQAvD_BwE

4.      Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases (NCEZID), Division of High-Consequence Pathogens and Pathology (DHCPP). Vaccine basics. Smallpox vaccine basic. Accessed from URL:

5.      The five stages of vaccine development. graphic-vaccine-development-1200x1850.png?itok=y0Cq0Vr2 accessed on december 1, 2020

6.      Young KD. Coronavirus vaccines: We address 3 big questions about safety, distribution and adoption. accessed from

7.      Centers for Disease Control and Prevention. Planning for a vaccine. frequently asked questions about COVID vaccination. accessed from ncov/vaccines/faq.html

8.      Bertin P, Nera K, Delouvée S. Conspiracy Beliefs, Rejection of Vaccination, and Support for hydroxychloroquine: A Conceptual Replication-Extension in the COVID19 Pandemic Context. Frontiers in psychology. 2020 Sep 18;11:2471. accessed from

9.      Institute of Medicine 2012. Adverse Effects of Vaccines: Evidence and Causality. Washington, DC: The National Academies Press. accessed from

10.    Wakefield A. MMR vaccine and Autism, The Lancet.

11.    Godlee Fiona. The fraud behind the MMR scare BMJ 2011; 342: d22 doi: accessed from

12.    Spooner MH. Measles outbreaks in the UK are linked to fears about the MMR vaccine. CMAJ. 2002 Apr 16; 166(8): 1075. PMCID: PMC100893. Accessed from URL:


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