Issue Vol:64, No:8 August, 2014


Psychological consequences of watching television news channels
Komal Daredia, Nosheen Zehra,

News media happens to be an integral part of modern life as it plays an informational as well as educational role. It helps people to update themself and be aware of the surroundings. Furthermore it keeps them conscious of the society and world in general.1 Television news ....

Original Articles

Utilization of systemic palliative chemotherapy at the end of life: a local experience
Essam Abdul Monem, Itrat Mehdi, Bassim Jaffar Al Bahrani, Ayman Mohammad Nada, Suad Al Kharusi,

Objective: To evaluate attitude towards using systemic chemotherapy near the end of life for cancer patients.
Methods: This retrospective study comprised data of all patients who died with cancer at the Medical Oncology Department of the National Oncology Centre, Muscat, Oman....

Knowledge, attitudes and beliefs of Turkish women towards blood donation
Save Dilsad, Ozlem Tanriover, Seyhan Hidiroglu, Yasar Gurbuz, Melda Karavus,

Objectives: To understand the knowledge, attitudes and beliefs of women towards blood donation and to help healthcare workers to plan steps to increase blood donation rates.
Methods: The qualitative study was conducted between January to May 2013 in two densely-populated dist....

Comparison of EMLA cream with rattles on reducing immunization pain in four months infants
Mahdi Basiri-Moghadam, Mojtaba Kianmehr, Saeid Pasban-Noghabi, Kokab Basiri-Moghadam,

Objective: To assess the effect of Eutectic Mixture of Local Anaesthetics cream and rattle on soothing the vaccination pain on four-month-infants.
Methods: The single blind randomised clinical trial was conducted from May 2012 to February 2013 at a clinic under the Gonabad Un....

To compare the accuracy of Prayer's sign and Mallampatti test in predicting difficult intubation in Diabetic patients
Mirza Mudassir Ali Baig, Fazal Hameed Khan,

Objective: To determine the accuracy of Prayer's sign and Mallampatti test in predicting difficult endotracheal intubation in diabetic patients.
Methods: The cross-sectional study was performed at Aga Khan University Hospital, Karachi, over a period from January 2009 to Apri....

The importance of apoptotic activity and plasma NT-proBNP levels in patients with acute exacerbation of decompensated heart failure and their relation to different drugs and comorbidities
Ayse CennetInce Sarimehmetoglu, Nazmi Gultekin, Emine Kucukates, Ahmet Yildiz, Cuneyt Kocas, Murat Ersanli,

Objective: To demonstrate the presence and importance of apoptotic activity in heart failure during acute exacerbations and to investigate the effects of different drugs used and co-morbidities on levels of N-Terminal pro-Brain Natriuretic Peptide and apoptotic activity on admission and du....

Prevalence of Methicillin Resistant Staphylococcus aureus in pyogenic community and hospital acquired skin and soft tissues infections
Muhammad Khurram Ahmad, Asma Asrar,

Objective: To determine the percentage and frequency of Methicillin Resistant Staphylococcus aureus in community and hospital-acquired pyogenic skin and soft tissue infections.
Methods: The descriptive cross-sectional study was conducted at the Dermatology Department of Combi....

Comparison of British Thoracic Society and American Thoracic Society reintroduction guidelines for anti-tuberculous therapy induced liver injury
Bader Faiyaz Zuberi, Faisal Faiyaz Zuberi, Nimrah Bader, Haris Alvi, Javeria Salahuddin,

Objective: To compare the efficacy of British Thoracic Society and American Thoracic Society guidelines for re-introduction of anti-tuberculous therapy after drug-induced liver injury, and to assess the ease of administration of each guideline on a scale of 1-10.
Methods: The....

Effectiveness of behavioural management on migraine in adult patients visiting family practice clinics: a randomized controlled trial
Swaleha Tariq Bhombal, Asma Usman, Mariam Ghufran,

Objectives: To assess the effectiveness of behavioural management in the treatment of migraine among adult patients.
Methods: The randomised control trial was conducted from August 2011 to August 2012 at the Aga Khan University Hospital, Karachi, in which adult patients aged ....

Assessing two methods of repair of duodenal defects, jeujenal serosal patch and jejunal pedicled flap, (an experimental animal study)
Bizhan Ziaian, Massood Hosseinzadeh, Behroz Nikravesh, Reza Roshanravan, Salar Rahimikazerooni, Ali Reza Safarpour, Sam Moslemi,

Objective: To evaluate the outcomes of jejunal serosal patch and jejunal pedicled flap procedures for the repair of duodenal injuries.
Methods: The experimental animal-model study was conducted at Shiraz University of Medical Sciences, Iran, in February 2013. Ten mixed....

Where does ergometrine stand in prevention of postpartum haemorrhage in caesarean section?
Ghazala Mahmud, Kiran Javaid, Nasira Tasnim, Arfa Tabassum, Kausar Tasneem Bangash,

Objective: To compare the safety and efficacy of 10 units of intravenous syntocinon alone with 10 units intravenous syntocinon and 0.25mg intramuscular ergometrine in the prevention of atonic uterine haemorrhage during caesarean section.
Method: The quasi-experimental study w....

Evaluation of premenstrual syndrome and quality of life in university students
Sevil Sahin, Keuser Ozdemir, Alaattin Unsal,

Objective: To determine the frequency of premenstrual syndrome, review associated factors and evaluate quality of life in university students.
Methods: The cross-sectional study was conducted at Sakarya University, Turkey, between October 25, 2012, and April 25, 2013. Premens....

The value of electroencephalography in differential diagnosis of altered mental status in emergency departments
Latif Duran, Kemal Balci, Turker Yardan, Celal Kati, Hizir Ufuk Akdemir, Sevdegul Karadas, Mehmet Altuntas,

Objective: To evaluate the value of electroencephalography in patients with altered mental status in emergency departments.
Methods: Demographical characteristics, types and aetiologies of seizures, and clinical outcomes of the patients were recorded. Patients were divided in....

Pakistan prevalence survey in acute pharyngitis
Suresh Kumar Rathi, Raeefuddin Ahmed,

Objective: To study the prevalence of Group A beta haemolytic Streptococcus in patients with acute pharyngitis and correlation of Modified Centor Score and Rapid Antigen Detection Test.
Methods: The multi-centre, prospective, cross-sectional study was conducted in 8 major cit....

Acute effect of insulin on guinea pig airways and its amelioration by pre-treatment with salbutamol
Mahjabeen Sharif, Bushra Tayyaba Khan, Khalida Ajmal, Mohammad Asim Anwar,

Objective: To study the magnitude of insulin-mediated airway hyper-reactivity and to explore the protective effects of salbutamol in inhibiting the insulin-induced airway hyper-responsiveness on tracheal smooth muscle of guinea pigs in vitro.
Methods: The quasi-experimental s....

Attribution of lifestyle risk factors in subjects with and without Impaired Fasting Glucose
Mehran Babanejad, Farid Najafi, Amir Hossein Hashemian, Eskandar Gholami Parizad, Ali Delpisheh, Khairollah Asadollahi,

Objective: To investigate the association between lifestyle risk factors and impaired fasting glucose level.
Methods: The large-scale, community-based, cross-sectional study was conducted in 2012 in Ilam province, Iran, and comprised 150 impaired fasting glucose cases and 450....

Review Articles

Review of diagnostic techniques of hepatic fibrosis
Sobia Hassan, Serajuddaula Syed, Shahnaz Imdad Kehar,

With increasing innovations aimed at the treatment of chronic liver disease (CLD), the precise staging of liver fibrosis is important to help establish efficacious management of disease activity in each patient. The development of biomarkers capable of non-invasive staging of fibrosis in the live....

Case Reports

Malignant transformations in Ovarian Teratomas: A report of four cases
Abdul Hannan, Umm-e-Kalsoom Awan, Neelam Siddiqui, Narjis Muzaffar,

Mature cystic teratoma (MCT) is a common ovarian neoplasm in young females. A secondary malignant transformation occurs rarely in cystic teratomas at an older age. These secondary malignant neoplasms most commonly are squamous cell carcinomas (SCCs). Various mechanisms are reported, but the exact....

Piriformis Syndrome - a rare cause of extraspinal sciatica
Shumaila Arooj, Muhammad Azeemuddin,

Piriformis syndrome is a rare entity resulting in severe unilateral isolated buttock pain shooting in nature, non discogenic in origin. MR imaging of pelvis plays an important role in such patients to see the normal anatomy of piriformis muscle and its relationship with sciatic nerve. A 35-year-o....

Treatment of tar burns: two case reports
Sevdegul Karadas, Hayriye Gonullu, Mehmet Resit Oncu, Hatice Kara, Huseyin Baltacioglu,

Hot tar burns are still a challenging clinical form because the removal of tar is very difficult for the emergency physician and there is no specified appropriate agent for the removal of tar. In this study, two patients with hot tar burns who were treated with diesel, sunflower oil and mayonnais....

Application of shear wave elastography in fine needle aspiration biopsy for thyroid nodule
Bu Yun Ma, Shyam Sundar Parajuly, Shu Xue Ying, Peng Yu Lan,

Ultrasound guided fine needle aspiration biopsy (FNAB) is the first-line procedure in diagnosing thyroid nodules. However, emerging studies have reported its unsatisfactory cell sample for cytology evaluation. In this case report, shear wave elastography (SWE) guided FNAB on a thyroid nodule is p....

Acute necrotising pancreatitis and acalculous cholecystitis: A rare presentation of leptospirosis
Sazlyna Mohd Sazlly Lim, Fankee Hoo, Wan Aliaa Wan Sulaiman, Vasudevan Ramachandran, Ching Siew-Mooi,

Leptospirosis typically presents with fever and thrombocytopenia, with or without jaundice. Acute necrotising pancreatitis and acalculous cholecystitis are rare presentations of this spirochetal infection. Here is the case of necrotising pancreatitis and acalculous cholecystitis associated with l....

Do we really need to panic in all acute vision loss in ICU? Acute angle-closure glaucoma
Ali Akal, Ahmet Kucuk, Funda Yalcin, Saban Yalcin,

Acute angle closure glaucoma is a sight-threatening situation characterized by a sudden and marked rise in intraocular pressure (IOP) due to obstruction of aqueous humour outflow. Many local (ocular drops, nasal and nebulized agents) and systemic drugs (e.g. atropine, adrenaline, ephedrine, some ....

Recurrent meningitis in a child with IgG3 subclass deficiency
Aysel Vehapoglu, Gamze Ozgurhan, Aysegul Dogan Demir, Selcuk Uzuner, Mustafa Atilla Nursoy, Serdar Turkmen,

Recurrent meningitis is an uncommon life-threatening condition. Here, the case of a 6-year-old boy is reported who had two episodes of meningitis with an IgG3 subclass deficiency. The boy had aseptic meningitis at the age of 3 years, followed by bacterial meningitis at the age of 4 years. Primary....

Student's Corner

Double outlet right ventricle, atrioventricular canal defect with severe pulmonary artery stenosis: a rare cyanotic congenital heart disease
Shoukat Ali Baig, Zara Saeed, Arsala Fatima, Hasina Chagani, Sina Aziz,

Double outlet right ventricle (DORV) is characterised by arousal of the aorta and the pulmonary vessel from the right ventricle, and is always accompanied by a ventricular septal defect (VSD). Our patient, a twenty days-old female child, presented to the Paediatrics Unit I of Civil Hospital, Kara....

Early vaccination: what dissuades parents from vaccinating their children?
Dania Aijaz Shah,

Madam, early vaccination is an effective means of preventing diseases ranging from common ones such as flu, pneumonia, measles, and mumps to some of the devastating sorts like polio, meningitis and cervical cancers.1 However, immunization facilities are yet to benefit a lar....

Letter to the Editor

Incessant cry - rare presentation of neonatal parotitis
Mukut Banerjee, Tarak Nath Ghosh, Sangita De,

Madam, An 18-day-old female neonate, otherwise healthy, presented with incessant cry for 2 days, increased during feeding. Baby was born out of non-consanguineous marriage. It was an institutional normal vaginal delivery, at term. The antenatal and postnatal period was uneventful. The baby was ex....

We can improve!
Qamrunnisa Hamdani Hanif,

Madam, a visit to the pediatrician's OPD can be enlightening! Most of the patients we see are those of viral flu, diarrhoea, typhoid, measles, chicken pox, pneumonia, tuberculosis, and viral hepatitis, and not to miss polio whose 59 alarming cases were detected in the year 2014, which has put a ....

The evidence of mother to child transmission of hepatitis B virus infection in Pakistan and the need for hepatitis B immunization policy change
Beuy Joob, Viroj Wiwanitkti,

Madam, the recent report on "mother to child transmission of hepatitis B virus infection and hepatitis B immunization" is very interesting.1 Qureshi et al. concluded that "hepatitis B vaccination given at 6, 10 and 14 weeks of birth is not sufficiently protec....

Apropos: Effects of papaya leaves on thrombocyte counts in dengue - a case report
Subhash Chandra Arya, Nirmala Agarwal,

Madam, we compliment the team of investigators at the Sunset Poly Clinic in Karachi, Pakistan for their management of Dengue virus (DENV) associated thrombocytopenia in the 23 year-old male by the five day recipe of Circa papaya leaves extract.1 We agree further well contro....

Evidence Based Medicine

Depression and risk of stroke in middle aged women
Adeel Ali Memon, Quratulain Nauman Shaikh, Ayeesha Kamran Kamal,

Why is this study important?
The burden of stroke is higher among women because they live longer, have higher rates of stroke in old age as compared to men and less physical performance after stroke. Although depression post stroke is well documented but depression as a conventional....

Reply to Comments

The evidence of mother to child transmission of hepatitis B virus infection in Pakistan and the need for hepatitis B immunization policy change
Huma Qureshi,

Madam, thank you for sending the comments on my paper.
I totally agree to the comments of the reader but would like to add that that birth dose of hepatitis B is recommended by WHO for all countries having HBV prevalence of >2% and Pakistan is one of them. Looking into three points that....

Learning Research

Reporting the results of a controlled trial
Naveed Zafar Janjua, Junaid Ahmad Bhatti, Faiza Rizwan,

Randomized controlled trials (RCTs) are considered the gold standard for evaluation of healthcare interventions. Biases introduced by inadequate methods, however, affect rigor of evidence from RCTs. Thus, a complete and transparent reporting of methods and results is needed to help readers to eva....

Recent Advances In Endocrinology

Thyroid disorders and diabetes
Sanjay Kalra,

Thyroid disorders and diabetes mellitus are two of the most common endocrine conditions, which occur with greater frequency along with each other. This communication describes current knowledge about these twin diseases. Epidemiology, clinical features, laboratory abnormalities, screening and the....

News & Events


Sindh Institute of Urology and Transplantation (SIUT), Karachi will celebrate 40 years of its services by holding an International Symposium on Recent Advances in Urology, Nephrology, GI Hepatology, Paediatrics, Transplantation & Bioethics from 8th to 12th December, 2015.Social and economic aspects of health care especially in a developing country will also be included.
Important Dates: Last date for Abstract submission:31st July 2015
Last Date for early registration: 30. September, 2015




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