Welcome to Journal Of Pakistan Medical Association
   Issue Vol:66, No:7 July, 2016
Editorial >>

Ramadan and diabetes: Holistic trial design

Fatema Jawad, Sanjay Kalra.

Extensive work has been done to analyze the safety of various modern glucose-lowering drugs during Ramadan fasting. This editorial suggests the use of validated scales of religiosity/spirituality as an adjunct to pre-Ramadan counselling and risk stratification. The editors also propose a holistic

Control of poisoning through product labeling of hazardous chemicals

Nadeem Ullah Khan, Arshad Iqbal, Sadaf Sheikh.

Acute poisoning and chemical exposure is a worrisome problem globally especially because of rapid industrialization and rapid increase in number and types of chemicals.1 According to the Chemical Abstracts Service (CAS) Registry, more than 83 million chemical substances are

Original Articles >>

Impact of emotional maltreatment on self esteem among adolescents

Sadia Malik, Aneeqa Kaiser.

Objective: To investigate the impact of emotional maltreatment on self-esteem among adolescents, and to see if gender makes a difference in this context.
Methods: The cross-sectional study was conducted from January to April 2014, and comprised adolescents in the age range of

Evaluation of QT parameters in patients of thalassaemia major with iron overload

Amna Faruqi, Syed Imran Ahmad, Syed Tousif Ahmed.

Objective: To study QT parameters in Thalassaemia Major patients and their association with serum ferritin levels.
Methods: This cross-sectional study was conducted at Ziauddin University, Karachi, from February 2013 to September 2014, and comprised patients of Thalassaemia M

Cross-sectional study on the endotoxin exposure and lung function impairment in the workers of textile industry near Lahore, Pakistan

Nadia Ghani, Anum Khalid, Arifa Tahir.

Objective: To examine the effects of airborne endotoxin on lung function impairment in exposure-response relationships among the workers of textile industry.
Methods: The cross-sectional study was conducted at Lahore College for Women University, Lahore, Pakistan, from Januar

Apoptosis kinetics at reperfusion period in patients with acute ST-Segment Elevation Myocardial Infarction undergoing primary percutaneous coronary intervention and treated with thrombolytic therapy

Nazmi Gultekin, Gulsum Bulut, Emine Kucukates, Ahmet Yildiz, Cuneyt Kocas, Leyla Bulut.

Objective: To evaluate the kinetics of cardiomyocyte apoptosis in patients undergoing primary percutaneous coronary intervention and thrombolytic therapy in order to elucidate the dark side of reperfusion injury.
Methods: The prospective descriptive study was conducted at Ist

Frequency of infection associated with ventriculo-peritoneal shunt placement

Ramesh Kumar, Syed Muneeb Younus, Abdul Haseeb, Muhammad Bilal, Qazi Muhammad Zeeshan, Junaid Ashraf.

Objective: To compare the frequency of infection in protocol-based and random ventriculo-peritoneal shunt placement in patients with hydrocephalus.
Methods: The prospective, observational study was conducted at Civil Hospital, Karachi, from October 2014 to March 2015, and com

Incidence of environmental and genetic factors causing congenital cataract in Children of Lahore

Shagufta Naz, Saima Sharif, Hafsa Badar, Farzana Rashid, Afshan Kaleem, Mehwish Iqtedar.

Objective: To check the incidence of environmental and genetic factors causing congenital cataract in infants.
Methods: The descriptive study was conducted at Layton Rahmatullah Benevolent Trust, Lahore, Pakistan, from October 2013 to April 2014, and comprised children under

Assessment of death anxiety among medical and surgery clinics patients of a teaching hospital

Sevilay Hintistan, Dilek Cilingir, Hilal Pekmezci.

Objective: To determine the level of death anxiety among inpatients in Medical and Surgery clinics.
Methods: The cross-sectional study was conducted at the Medical and Surgery clinics of the University Hospital of Trabzon, Turkey, from June 15 to October 15, 2014. Data was ga

Risk factors and clinical outcomes for vancomycin-resistant enterococcus bacteraemia in hospitalised cancer patients in Pakistan: A case-control study

Nasim Akhtar, Faisal Sultan, Summiya Nizamuddin, Waleed Zafar.

Objective: To compare the risk factors and outcomes of vancomycin-resistant enterococcus with vancomycin-sensitive enterococcus bacteraemia among hospitalised cancer patients.
Methods: The retrospective, case-control study was conducted at Shaukat Khanum Memorial Cancer Hosp

Role of sodium-restricted dietary approaches to control blood pressure in Pakistani hypertensive population

Sajida Naseem, Haider Ghazanfar, Salman Assad, Ali Ghazanfar.

Objective: To assess the change in systolic and diastolic blood pressure in post-interventional phase through \\dietary approaches to stop hypertension/salt-restricted diet.

Methods: This randomised co

Analysis of dental erosion induced by different beverages and validity of equipment for identifying early dental erosion, in vitro study

Rafey Ahmad Jameel, Shah Salman Khan, Zubaidah Hj Abdul Rahim, Marina Mohd Bakri, Saima Siddiqui.

Objective: To understand early dental erosion induced by different beverages and the equipment for its detection.

Methods: The study was conducted at the University Malaya Medical Centre, Kuala Lumpur, M

Pattern of firearm injuries in head and neck regions at a tertiary care hospital

Fazal i Wahid, Muhammad Riaz Khan, Muhammad Masood Khan, Naseem-ul- Haq, Muhammad Javaid, Habib-ur- Rehman, Bakht Zada.

Objective: To determine the characteristics of firearm injuries on head and neck in patients presenting to the Ear Nose and Throat Department of a tertiary care hospital.

Methods: This prospective, cross

Translation, validation and effectiveness of self-care inventory in assessing adherence to diabetes treatment

Tuba Mumtaz, Samsaam Ali Haider, Jamil Ahmad Malik, Annette Marie La Greca.

Objectives: To evaluate the efficacy of an Urdu translation of Self Care Inventory for measuring adherence to diabetes treatment.

Method: The correlational cross-sectional study was conducted in October

Amelioration of acetaminophen induced hepatotoxicity by methanolic extract of pomegranate peels in rats

Nadia Ahmad, Mohammad Tahir, Khalid Perwez Lone.

Objective: To observe the ameliorating effect by methanolic extract of pomegranate peel in acetaminophen-induced hepatotoxicity.

Methods: The randomised controlled study was conducted from July 2013 to J

Changing spectrum of traumatic head injuries: Demographics and outcome analysis in a tertiary care referral center

Muhammad Junaid, Mamoon-ur-Rashid, Afeera Afsheen, Ayesha Tahir, Syed Sarmad Bukhari, Anisa Kalsoom.

Objective: To determine the causes, epidemiological characteristics and clinical outcomes related to cases of head trauma.

Methods: The retrospective study was conducted at Combined Military Hospital, Qu

Effects of ballet training of children in Turkey on foot anthropometric measurements and medial longitudinal arc development

Sevgi Anar Ozdinc, Fatma Nesrin Turan.

Objective: To investigate the effects of ballet training on foot structure and the formation of the medial longitudinal arc in childhood, and the association of body mass index with structural change secondary to ballet training.

Review Articles >>

Dengue viral infections in Pakistan and other Asian countries: a comprehensive review

Muhammad Zubair, Muhammad Ashraf, Aitezaz Ahsan, Noor-ul-ain Nazir, Hina Hanif, Haider Ali Khan.

Infections due to Dengue virus are widespread throughout the world. Disease starts with mild flu like sickness to a severe intricate condition which results in the death of the patient. Dengue illness has high morbidity and mortality in Pakistan as well as in other Asian countries. The Review art

Short Communication >>

Spatial distribution and accessibility to public sector tertiary care teaching hospitals in Karachi: A Geographic Information Systems application

Masood Ali Shaikh, Mir Shabbar Ali.

Optimal utilization of specialized curative healthcare services is contingent on spatial access to tertiary-care hospitals by the targeted population. The objectives of this study were to determine the spatial distribution of public sector tertiary-care teaching hospitals in Karachi, and to use G

Case Reports >>

Risk continues: Very late manifestation of helicobacter pylori at gastric augmented bladder

Rohsan Ozcan, Sinan Celayir, Mehmet Elicevik, Sergulen Dervisoglu.

Helicobacter Pylori was previously demonstrated at gastric patch after gastrocystoplasty and a possible relationship with acid-haematuria syndrome was established after symptomatic relief by medical treatment. We present the long term outcome of a male bladder exstrophy patient a

Hair-thread tourniquet syndrome originating from a haemangioma in an adult patient

Osman Mahir Okur, Abuzer Coskun, Afsin Emre Kayipmaz, Sedat Ozbay, Cemil Kavalci, Ummu Gulsum Kocalar.

Hair-thread tourniquet syndrome is an emergency condition rarely encountered since its first description, and it may be potentially dangerous unless treated. The potential hazard of the condition stems from hair strands wrapping around and strangulating various body processes such as fingers, pen

Spontaneous uterine rupture at 28 weeks: A case report

Mahreen Rasool, Imrana Masroor, Shafia Shakoor, Shama Munim.

Spontaneous Uterine rupture is associated with massive intra-peritoneal bleed which can be fatal if not recognized. We report a case of 32 year old multigravida at 28 weeks of gestation with history of liver cysts, previous caesarean and uterine curettage, who presented with acute abdominal pain

Primary angiosarcoma of neck nodes with bony metastasis - A case report

Shabbir Hussain Ashiq Ali, Mohammad Jawaid Akhtar Mallick, Ayesha Javed, Abdul Hafeez Lakhan.

This is a case of a 30 year old female who presented in February 2012 with a large painless left neck swelling since 5 months. Her biopsy was done but the result was inconclusive. Later on after proper staging workup it was found to be bony metastatic disease. Her repeated biopsy showed spindle c

Renal aspergilloma presenting with pelvi-ureteric junction Obstruction (PUJO)

Syed Rabi Ullah, Anila Jamshaid, Syed Zafar Zaidi.

Primary renal aspergillosis, though a rare entity, is still seen in immune compromised individuals. Renal aspergillosis may lead to formation of focal abscesses, fungal bezoars and may cause ureteric obstruction. Treatment involves stabilization of patient and removal of fungal bezoars along with

T-cell/histiocyte-rich large B-cell lymphoma of stomach

Figen Barut, Nilufer Onak Kandemir, Banu Dogan Gun, Sukru Oguz Ozdamar.

T-cell/histiocyte-rich large B-cell lymphoma is an unusually encountered lymphoid neoplasm of stomach with aggressive course, and is an uncommon morphologic variant of diffuse large B-cell lymphoma. An ulcerated mass, 7x5x1 cm in size was observed within the gastrectomy specimen of a 76-year-old

Letter to the Editor >>

Impact of consumption of canned food during pregnancy

Maryam Pyar Ali Lakhdir.

Madam, as the world moves towards modernisation, the preference forcanned foods is increasing day-by-day especially during pregnancy when a woman wants to nurture her foetus with the best quality of food available in the market. Such food include salad toppings with frozen vegetables, sauces and

Pubmed commons: Pros and cons

Syed Askari Hasan, Irfan Masood, Zohaib Mumtaz.

Madam, I want to draw your attention to a notable addition in the field of medical literature; Pub-med Commons. This is an innovative project by Pub-med which provides an interface to the consumers of research to comment on any pub-med indexed article and receive feedback from the authors instant

Recent Advances In Endocrinology >>

Choosing injectable therapy: The metabolic fulcrum

Sanjay Kalra, Yashdeep Gupta.

This clinical decision making hypothesis utilizes the metabolic fulcrum based approach to classify persons with diabetes into three categories: predominantly catabolic, eubolic, and predominantly [maladaptive] anabolic. This systematic arrangement helps define choice of injectable therapy in type

Pilot Study >>

Tobacco control laws in Pakistan and their implementation: A pilot study in Karachi

Javaid Ahmed Khan, Abdul Malik Amir Humza Sohail, Muhammad Arslan Arif Maan.

Objectives: In order to limit the high prevalence of tobacco use in Pakistan various tobacco control laws have been implemented. The objective of this study is to serve as a pilot study to assess the implementation of these laws in the largest city of Pa

Oncologists awareness about bisphosphonate related osteonecrosis of the jaws

Mehmet Fatih Senturk, Emre Cimen, Aysegul Mine Tuzuner Oncul, Mine Cambazoglu.

Objective: To evaluate the oncologists thoughts about the positive and adverse effects of bisphosphonates, drug holiday and the awareness about BRONJ.

Methods: A written questionnaire was sent to 7 hospi

Primary Care Diabetes >>

Prevention of lipohypertrophy

Sanjay Kalra, Yashdeep Gupta.

Lipohypertrophy is an important insulin injection site reaction, which has clinically significant sequelae, including a greater risk of glycaemic variability and higher insulin dose requirement. This article describes the prevention of lipohypertrophy, using the concept of levels of prevention. I

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